Future progress on human development and planetary health depends on solving central banks needing stronger cyber defence. Conventional approaches have proven insufficient. The required intervention must integrate community knowledge, data and appropriate technology while remaining affordable, privacy-preserving and operable with minimal external support. Strong solutions will articulate measurable impact metrics, risk mitigation strategies, and a plan for sustained operation by local actors after the pilot phase.
central
banks
needing
stronger
cyber
technology-computing
digital detox remaining hard remains one of the most urgent challenges of our time. Systems currently in place are inadequate for the scale and complexity of the problem. A successful approach must work where resources are scarcest and demonstrate clear, measurable results. It should identify possible harms, respect local agency, and show how the solution can be maintained and expanded by the communities it is meant to serve.
digital
detox
remaining
hard
implementing
technology-computing
AI and laboratory automation can identify promising compounds that fail during scale-up, processing, or deployment. The open problem is connecting discovery models to cost, supply, safety, and lifecycle constraints. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
discovery
materials
systems
predict
real-world
manufacturability
low-income
communities
identify
deployment
economics-resources
climate-environment
society-governance
quantum
infrastructure
science-space
governance
Future progress on human development and planetary health depends on solving software updates stopping. Conventional approaches have proven insufficient. The required intervention must integrate community knowledge, data and appropriate technology while remaining affordable, privacy-preserving and operable with minimal external support. Strong solutions will articulate measurable impact metrics, risk mitigation strategies, and a plan for sustained operation by local actors after the pilot phase.
software
updates
stopping
strengthening
global
technology-computing
Future challenges such as AI, climate engineering, cyber conflict, and biotechnology cross borders but may be governed by incompatible national rules. The open problem is creating minimum safety floors without requiring complete political agreement. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
coordination
countries
reject
shared
standards
low-income
communities
future
such
climate-environment
economics-resources
society-governance
systems
infrastructure
quantum
science-space
safe
Automation may reduce routine collaboration and informal learning, especially for remote and platform workers. Future work design must preserve mentorship, belonging, collective problem-solving, and psychological health. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
europe
germany
preventing
social
isolation
highly
automated
workplaces
under
geopolitical
fragmentation
design
economics-resources
climate-environment
society-governance
systems
quantum
open
United States, North America
Automated scheduling, evaluation, pricing, and dismissal may shape work without a visible manager. The unresolved problem is giving workers collective voice over systems that are proprietary, dynamic, and difficult to audit. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
north-america
united-states
systems
worker
representation
inside
algorithmic
management
low-income
communities
work
automated
economics-resources
climate-environment
society-governance
quantum
infrastructure
Future crops, microbes, and fermentation systems may depend on patented seeds, strains, software, or inputs. The open problem is preserving farmer and national autonomy while rewarding useful innovation. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
africa
kenya
preventing
food-system
dependence
proprietary
biological
platforms
low-income
communities
future
crops
economics-resources
climate-environment
society-governance
systems
quantum
Algorithmically designed foods may optimize cost, taste, shelf life, or emissions while neglecting long-term health and cultural acceptability. The challenge is creating transparent nutritional and ethical evaluation. The problem cannot be solved by one jurisdiction because people, ecosystems, data, supply chains, or risks cross national boundaries. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
africa
kenya
supply-chain
foods
nutrition
standards
ai-designed
borders
algorithmically
designed
may
optimize
cost
economics-resources
climate-environment
society-governance
systems
open
Brazil, South America
Automated rental, mortgage, insurance, and zoning systems may reproduce historical exclusion through apparently neutral variables. Cities need transparent testing, appeals, and anti-discrimination safeguards. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
south-america
brazil
preventing
algorithmic
segregation
housing
allocation
low-income
communities
automated
rental
mortgage
economics-resources
climate-environment
society-governance
systems
infrastructure
platform companies keeping most of the value remains one of the most urgent challenges of our time. Systems currently in place are inadequate for the scale and complexity of the problem. A successful approach must work where resources are scarcest and demonstrate clear, measurable results. It should identify possible harms, respect local agency, and show how the solution can be maintained and expanded by the communities it is meant to serve.
platform
companies
keeping
value
building
technology-computing
open
Brazil, South America
Future cities may depend on private platforms operating transit, energy, housing, communication, and public-space services. Strong public-interest rules are needed when essential services are controlled through private systems. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
south-america
brazil
services
urban
governance
privately
operated
public
infrastructure
low-income
communities
private
economics-resources
society-governance
climate-environment
systems
quantum
cyberbullying harming children remains one of the most urgent challenges of our time. Systems currently in place are inadequate for the scale and complexity of the problem. A successful approach must work where resources are scarcest and demonstrate clear, measurable results. It should identify possible harms, respect local agency, and show how the solution can be maintained and expanded by the communities it is meant to serve.
cyberbullying
harming
children
building
effective
technology-computing
Future progress on human development and planetary health depends on solving digital systems that exclude people without phones or internet. Conventional approaches have proven insufficient. The required intervention must integrate community knowledge, data and appropriate technology while remaining affordable, privacy-preserving and operable with minimal external support. Strong solutions will articulate measurable impact metrics, risk mitigation strategies, and a plan for sustained operation by local actors after the pilot phase.
systems
digital
exclude
people
without
technology-computing
Decision-makers lack integrated, high-resolution models of ocean chemistry, biology, currents, and human activity. The open problem is building trustworthy systems that support decisions without creating false confidence from incomplete data. The solution must produce useful coordination and accountability while minimizing collection of sensitive personal and behavioral data. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
europe
norway
real-time
marine
ecosystem
digital
twins
mass
surveillance
data
decision-makers
lack
society-governance
economics-resources
climate-environment
systems
without
Decision-makers lack integrated, high-resolution models of ocean chemistry, biology, currents, and human activity. The open problem is building trustworthy systems that support decisions without creating false confidence from incomplete data. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
europe
norway
real-time
marine
ecosystem
digital
twins
under
geopolitical
fragmentation
data
decision-makers
economics-resources
society-governance
systems
climate-environment
infrastructure
Decision-makers lack integrated, high-resolution models of ocean chemistry, biology, currents, and human activity. The open problem is building trustworthy systems that support decisions without creating false confidence from incomplete data. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
asia
philippines
real-time
marine
ecosystem
digital
twins
low-income
communities
decision-makers
lack
integrated
economics-resources
climate-environment
systems
society-governance
infrastructure
open
United States, North America
Autonomous spacecraft may make split-second avoidance decisions using imperfect data and proprietary software. The unresolved problem is assigning responsibility, proving fault, and compensating affected parties across jurisdictions. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
north-america
united-states
autonomous
spacecraft
liability
collisions
under
geopolitical
fragmentation
data
may
make
economics-resources
climate-environment
society-governance
systems
infrastructure
Autonomous spacecraft may make split-second avoidance decisions using imperfect data and proprietary software. The unresolved problem is assigning responsibility, proving fault, and compensating affected parties across jurisdictions. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
autonomous
spacecraft
liability
collisions
low-income
communities
may
make
split-second
avoidance
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
science-space
open
Brazil, South America
Genomic medicine could improve treatment while enabling insurers, employers, states, or platforms to infer sensitive traits. The challenge is ensuring people benefit from precision medicine without losing control over biological information. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
south-america
brazil
medicine
personalized
genetic
discrimination
low-income
communities
genomic
improve
treatment
while
economics-resources
climate-environment
society-governance
systems
quantum