Wearable and implantable sensors will generate continuous health data that is underused.
open
Global / Unspecified, Global
Over the next 10–20 years, biosensors will track vital signs, metabolites, and behaviours, but analytics and integration into care will lag. Edge-computing and clinically validated algorithms will be needed.
will
wearable
implantable
sensors
generate
technology-computing
Citation ID: WS02058
Title: Wearable and implantable sensors will generate continuous health data that is underused.
URL: https://www.worldsolve.org/index.php?api=problem&id=2058
Global bio-surveillance systems will need to detect engineered threats as well as natural ones.
open
Global / Unspecified, Global
Advances in synthetic biology may blur the line between accidental and deliberate outbreaks. Genomic anomaly detection and secure reporting pipelines could help.
global
bio
surveillance
systems
will
other
Citation ID: WS02059
Title: Global bio-surveillance systems will need to detect engineered threats as well as natural ones.
URL: https://www.worldsolve.org/index.php?api=problem&id=2059
Antimicrobial resistance in low-resource settings will be exacerbated by counterfeit and substandard drugs.
open
Global / Unspecified, Global
Poor-quality medicines accelerate resistance and treatment failure. Track-and-trace systems and quality-testing infrastructure are needed.
resistance
antimicrobial
low
resource
settings
health-biology
Citation ID: WS02060
Title: Antimicrobial resistance in low-resource settings will be exacerbated by counterfeit and substandard drugs.
URL: https://www.worldsolve.org/index.php?api=problem&id=2060
Human longevity research may widen socio-economic divides in lifespan.
open
Global / Unspecified, Global
Access to anti-ageing interventions could be skewed toward wealthy groups without deliberate policy. Equity-oriented regulation and public programmes will be required.
human
longevity
research
may
widen
society-governance
Citation ID: WS02061
Title: Human longevity research may widen socio-economic divides in lifespan.
URL: https://www.worldsolve.org/index.php?api=problem&id=2061
Climate-induced expansion of tick and mosquito habitats will change disease geography.
open
Global / Unspecified, Global
Lyme disease, dengue, and other infections may reach new regions. Integrated vector-surveillance and control platforms will be crucial.
will
disease
climate
induced
expansion
health-biology
Citation ID: WS02062
Title: Climate-induced expansion of tick and mosquito habitats will change disease geography.
URL: https://www.worldsolve.org/index.php?api=problem&id=2062
AI-designed drugs will require new regulatory science approaches.
open
Global / Unspecified, Global
Models may generate candidate molecules rapidly, challenging traditional assessment. Simulation-based validation and adaptive regulatory frameworks will be needed.
will
regulatory
designed
drugs
require
other
Citation ID: WS02063
Title: AI-designed drugs will require new regulatory science approaches.
URL: https://www.worldsolve.org/index.php?api=problem&id=2063
Future organ shortage crises may persist despite advances in regenerative medicine.
open
Global / Unspecified, Global
Bioprinting and stem-cell therapies may not scale fast enough to meet demand. Organ-allocation optimisation and cross-border sharing platforms remain important.
organ
may
future
shortage
crises
health-biology
Citation ID: WS02064
Title: Future organ shortage crises may persist despite advances in regenerative medicine.
URL: https://www.worldsolve.org/index.php?api=problem&id=2064
Chronic exposure to microplastics and environmental toxins may drive new disease patterns.
open
Global / Unspecified, Global
Emerging evidence suggests links to endocrine and immune disruption. Long-term exposure cohorts and mechanistic toxicology are required.
exposure
chronic
microplastics
environmental
toxins
climate-environment
Citation ID: WS02065
Title: Chronic exposure to microplastics and environmental toxins may drive new disease patterns.
URL: https://www.worldsolve.org/index.php?api=problem&id=2065
Personalised vaccines and immunotherapies will challenge cold-chain and delivery logistics.
open
Global / Unspecified, Global
Tailored biologics may require complex supply chains. Logistics-optimisation tools and modular manufacturing will be needed.
will
logistics
personalised
vaccines
immunotherapies
mathematics-logic
Citation ID: WS02066
Title: Personalised vaccines and immunotherapies will challenge cold-chain and delivery logistics.
URL: https://www.worldsolve.org/index.php?api=problem&id=2066
Data-poor regions risk being left out of global health AI advances.
open
Global / Unspecified, Global
Algorithms trained on high-income populations may not generalise to under-sampled groups. Inclusive data-collection initiatives and equity-centric model evaluation are necessary.
data
poor
regions
risk
being
technology-computing
Citation ID: WS02067
Title: Data-poor regions risk being left out of global health AI advances.
URL: https://www.worldsolve.org/index.php?api=problem&id=2067
Climate change is rapidly transforming Antarctica’s ice and ocean systems.
open
Antarctica / Unspecified, Antarctica
Rising temperatures and changing winds are destabilising ice shelves and altering Southern Ocean circulation, with global implications for sea-level rise and extreme weather. High-resolution coupled climate–ice models and sustained observation networks are needed to predict these changes.
ice
climate
ocean
change
rapidly
climate-environment
Citation ID: WS01963
Title: Climate change is rapidly transforming Antarctica’s ice and ocean systems.
URL: https://www.worldsolve.org/index.php?api=problem&id=1963
We lack precise projections of Antarctic ice-sheet collapse and associated sea-level rise.
open
Antarctica / Unspecified, Antarctica
Uncertainties in ice dynamics, bedrock conditions, and ocean–ice interactions make it hard to forecast tipping points and metres of future sea-level rise. Better grounding-zone measurements and data-assimilation tools could sharpen projections.
ice
projections
sea
level
rise
other
Citation ID: WS01964
Title: We lack precise projections of Antarctic ice-sheet collapse and associated sea-level rise.
URL: https://www.worldsolve.org/index.php?api=problem&id=1964
Antarctic ecosystems face emerging threats from warming, acidification, and changing sea ice.
open
Antarctica / Unspecified, Antarctica
Penguin, krill, and seabird populations are already shifting or declining as habitats change and food webs reorganise. Long-term ecological monitoring and ecosystem-modelling platforms are needed to guide conservation.
antarctic
ecosystems
face
emerging
threats
mathematics-logic
Citation ID: WS01965
Title: Antarctic ecosystems face emerging threats from warming, acidification, and changing sea ice.
URL: https://www.worldsolve.org/index.php?api=problem&id=1965
The Southern Ocean’s role in heat and carbon uptake is still poorly constrained.
open
Antarctica / Unspecified, Antarctica
Antarctic waters absorb large fractions of excess heat and CO2, yet models disagree on future behaviour and feedbacks. Expanded biogeochemical observing systems and process studies can refine global climate models.
heat
southern
ocean
role
carbon
climate-environment
Citation ID: WS01966
Title: The Southern Ocean’s role in heat and carbon uptake is still poorly constrained.
URL: https://www.worldsolve.org/index.php?api=problem&id=1966
Emerging pathogens and biosecurity risks threaten Antarctic wildlife and research stations.
open
Antarctica / Unspecified, Antarctica
Human presence and warming conditions may introduce new diseases to previously isolated species and communities. Robust biosecurity protocols, surveillance tools, and response plans are required.
biosecurity
emerging
pathogens
risks
threaten
health-biology
Citation ID: WS01967
Title: Emerging pathogens and biosecurity risks threaten Antarctic wildlife and research stations.
URL: https://www.worldsolve.org/index.php?api=problem&id=1967
Antarctic tourism is growing without fully tested sustainability and safety standards.
open
Antarctica / Unspecified, Antarctica
More ships and visitors increase risks of pollution, wildlife disturbance, and accidents in fragile environments. Data-driven tourism management systems and binding guidelines could reduce impact.
tourism
antarctic
growing
without
fully
climate-environment
Citation ID: WS01968
Title: Antarctic tourism is growing without fully tested sustainability and safety standards.
URL: https://www.worldsolve.org/index.php?api=problem&id=1968
Fisheries in the Southern Ocean, including krill, risk overexploitation.
open
Antarctica / Unspecified, Antarctica
Demand for krill-based products and fish drives fleets into sensitive ecosystems that underpin Antarctic food webs. Improved stock assessment and real-time monitoring platforms can inform precautionary management.
krill
fisheries
southern
ocean
including
other
Citation ID: WS01969
Title: Fisheries in the Southern Ocean, including krill, risk overexploitation.
URL: https://www.worldsolve.org/index.php?api=problem&id=1969
Governance under the Antarctic Treaty System faces new geopolitical pressures.
open
Antarctica / Unspecified, Antarctica
Shifts in global power, resource interest, and security concerns challenge consensus-based environmental governance. Scenario-analysis and compliance-monitoring tools can help strengthen the regime.
governance
under
antarctic
treaty
system
society-governance
Citation ID: WS01970
Title: Governance under the Antarctic Treaty System faces new geopolitical pressures.
URL: https://www.worldsolve.org/index.php?api=problem&id=1970
Governance under the Antarctic Treaty System faces new geopolitical pressures. This variant focuses on data, monitoring, and measurement challenges.
open
Antarctica / Unspecified, Antarctica
Shifts in global power, resource interest, and security concerns challenge consensus-based environmental governance. Scenario-analysis and compliance-monitoring tools can help strengthen the regime.
governance
monitoring
under
antarctic
treaty
society-governance
Citation ID: WS01971
Title: Governance under the Antarctic Treaty System faces new geopolitical pressures. This variant focuses on data, monitoring, and measurement challenges.
URL: https://www.worldsolve.org/index.php?api=problem&id=1971
We lack comprehensive data on human footprint and cumulative impacts in Antarctica.
open
Antarctica / Unspecified, Antarctica
Science, tourism, and fishing activities leave infrastructure, pollution, and disturbance, but their combined effects are under-studied. Spatial-impact mapping and cumulative-effects assessment platforms are needed.
cumulative
lack
comprehensive
data
human
technology-computing
Citation ID: WS01972
Title: We lack comprehensive data on human footprint and cumulative impacts in Antarctica.
URL: https://www.worldsolve.org/index.php?api=problem&id=1972
