Addressing more powerful and destructive storms is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
powerful
destructive
storms
2030
establishing
mathematics-logic
Addressing widespread destruction of wildlife habitats is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
widespread
destruction
wildlife
habitats
2030
mathematics-logic
Removing debris may require technologies capable of approaching, manipulating, or disabling other spacecraft. The challenge is creating verification and trust mechanisms so debris removal does not become covert anti-satellite capability. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
science-space
debris
removal
technologies
space
dual-use
low-income
communities
removing
may
require
technology-computing
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
Addressing marine animals dying after ingesting plastic is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
marine
animals
dying
after
ingesting
climate-environment
Addressing high vehicle emissions damaging health and climate is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
high
vehicle
emissions
damaging
health
climate-environment
Addressing people forced to sleep on the streets is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
people
forced
sleep
streets
2030
mathematics-logic
Modern economies rely on precise timing for finance, telecom, energy, and navigation. Future systems need resilient alternatives to single-source satellite timing during cyberattacks, solar storms, and geopolitical crises. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
science-space
asia
india
timing
secure
space-based
terrestrial
disruptions
low-income
communities
modern
economies
rely
technology-computing
economics-resources
climate-environment
society-governance
systems
Addressing unsafe and hazardous working conditions is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
unsafe
hazardous
working
conditions
2030
mathematics-logic
Addressing widespread diseases caused by contaminated water is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
widespread
diseases
caused
contaminated
water
mathematics-logic
Astronomy, cultural practices, wildlife, and human sleep may be affected by large satellite fleets. A workable solution must reconcile connectivity goals with brightness limits, orbital design, and international compliance. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
science-space
satellite
preserving
dark
skies
during
expansion
low-income
communities
solution
technology-computing
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
safe
Lunar infrastructure and resource extraction could create new strategic inequalities. The challenge is developing rules that enable science and commercial activity while protecting shared interests and preventing territorial competition. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
asia
india
lunar
equitable
access
scientific
resources
low-income
communities
create
infrastructure
resource
technology-computing
climate-environment
society-governance
systems
quantum
Autonomous spacecraft may make split-second avoidance decisions using imperfect data and proprietary software. The unresolved problem is assigning responsibility, proving fault, and compensating affected parties across jurisdictions. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
autonomous
spacecraft
liability
collisions
low-income
communities
may
make
split-second
avoidance
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
science-space
open
United States, North America
Thousands of satellites may provide connectivity while increasing collision risk, radio interference, light pollution, and disposal complexity. The challenge is creating enforceable coordination and end-of-life standards across commercial and state operators. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
climate-environment
north-america
united-states
managing
orbital
congestion
mega-constellations
low-income
communities
thousands
satellites
may
provide
technology-computing
economics-resources
society-governance
systems
quantum
open
Brazil, South America
Research environments may unintentionally create or amplify resistance traits that escape through waste, personnel, or supply chains. Robust solutions must combine laboratory engineering, surveillance, waste treatment, and international reporting. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
south-america
brazil
supply-chain
resistance
controlling
antimicrobial
synthetic
biology
laboratories
low-income
communities
research
create
technology-computing
climate-environment
society-governance
systems
Industrial agriculture, pollution, and habitat loss may eliminate microorganisms with future medical and ecological value before they are studied. The challenge is creating ethical, distributed microbial conservation infrastructure. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
health-biology
microbial
future
preserving
diversity
medicine
low-income
communities
industrial
agriculture
pollution
technology-computing
economics-resources
climate-environment
society-governance
systems
infrastructure
quantum
Large-scale fermentation may compete with food, land, and water if it depends on agricultural inputs. Future systems need safe, affordable, low-carbon feedstocks that do not shift environmental burdens to poorer regions. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
climate-environment
feedstocks
biomanufacturing
non-food
low-income
communities
large-scale
fermentation
may
compete
food
technology-computing
economics-resources
society-governance
systems
infrastructure
quantum
safe
open
Brazil, South America
Genomic medicine could improve treatment while enabling insurers, employers, states, or platforms to infer sensitive traits. The challenge is ensuring people benefit from precision medicine without losing control over biological information. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
south-america
brazil
medicine
personalized
genetic
discrimination
low-income
communities
genomic
improve
treatment
while
economics-resources
climate-environment
society-governance
systems
quantum
Engineered microbes, insects, crops, and gene drives may offer major ecological benefits but could spread beyond intended boundaries. The unresolved problem is developing reversible, monitorable, and internationally governed release frameworks. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
release
engineered
safe
environmental
organisms
low-income
communities
microbes
insects
crops
technology-computing
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
open
Brazil, South America
Future outbreaks may involve pathogens for which no profitable commercial market exists. A useful solution requires distributed manufacturing, adaptable platforms, pre-negotiated procurement, and equitable access before an outbreak occurs. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
south-america
brazil
manufacturing
pathogens
market
rapid
vaccine
existing
low-income
communities
solution
future
technology-computing
climate-environment
society-governance
systems
quantum
Biological design tools are becoming more accessible while oversight remains fragmented across countries and institutions. The challenge is detecting dangerous activity without suppressing legitimate research or creating an intrusive global surveillance system. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
monitoring
synthetic
biology
risk
low-income
communities
research
biological
design
technology-computing
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
science-space