World Solve

Future progress on human development and planetary health depends on solving systematic exclusion of girls from education. Conventional approaches have proven insufficient. The required intervention must integrate community knowledge, data and appropriate technology while remaining affordable, privacy-preserving and operable with minimal external support. Strong solutions will articulate measurable impact metrics, risk mitigation strategies, and a plan for sustained operation by local actors after the pilot phase.

Future progress on human development and planetary health depends on solving schools located too far for many children to reach. Conventional approaches have proven insufficient. The required intervention must integrate community knowledge, data and appropriate technology while remaining affordable, privacy-preserving and operable with minimal external support. Strong solutions will articulate measurable impact metrics, risk mitigation strategies, and a plan for sustained operation by local actors after the pilot phase.

Future progress on human development and planetary health depends on solving extreme poverty affecting more than 700 million people. Conventional approaches have proven insufficient. The required intervention must integrate community knowledge, data and appropriate technology while remaining affordable, privacy-preserving and operable with minimal external support. Strong solutions will articulate measurable impact metrics, risk mitigation strategies, and a plan for sustained operation by local actors after the pilot phase.

Current approaches to affordable diagnostics and treatments for the leading causes of maternal mortality either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to solutions for providing safe and accessible public transport in rapidly growing secondary cities either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

The absence of robust, context-adapted solutions for governance frameworks ensuring that advances in longevity science benefit all socioeconomic groups creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

The absence of robust, context-adapted solutions for technologies enabling precise and low-impact application of agricultural inputs creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Current approaches to technologies enabling the continuous monitoring of air quality and its health impacts at high resolution either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to cognitive and social interventions that improve collective problem-solving under uncertainty either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Achieving carbon-negative cementitious binders setting in saline conditions at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Models may generate candidate molecules rapidly, challenging traditional assessment. Simulation-based validation and adaptive regulatory frameworks will be needed.

The absence of robust, context-adapted solutions for education approaches that build the capacity of local institutions to manage climate risks creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Top-down planning can ignore local needs. Participatory approaches can improve outcomes.

Millions live in slums lacking secure tenure, clean water, or sanitation despite being near major urban economic centers. Incremental slum-upgrading programs are more effective and humane than demolition-based approaches.

Cities are growing faster than governments can build roads, utilities, and housing, leading to chronic service shortfalls. Incremental, modular urban planning approaches could help cities adapt more affordably.

Groups like Boko Haram and al-Shabaab exploit weak governance and poverty to recruit and control territory. Community-resilience programs paired with local economic opportunity have shown more success than military approaches alone.

The absence of robust, context-adapted solutions for solutions for safe long-term storage and monitoring of captured carbon dioxide creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Recurrent bacterial vaginosis affects a meaningful share of women despite standard treatment, suggesting current approaches don't fully address the underlying imbalance causing it. A more effective long-term prevention method remains needed.

The vast majority of autoimmune disease diagnoses occur in women, and the biological reasons behind this imbalance remain only partially understood. A clearer answer could open new treatment approaches for both sexes.

Lung cancer screening guidelines are generally built around smoking history, but a meaningful share of cases occur in people who never smoked at all and often go undetected until later stages. Better screening approaches for this group remain underdeveloped.