World Solve

Despite regulation added after every major crash, financial systems keep finding new ways to become unstable. We still don't have a reliable way to prevent the next one before it happens.

Billions of dollars in foreign aid have flowed for decades, yet the gap between wealthy and poor nations remains wide. This suggests aid alone isn't the missing piece, and a better approach is still needed.

Maternal death rates in some parts of the world remain drastically higher than in wealthy nations, despite childbirth being a universal human experience. Making safe childbirth truly global remains an unmet basic need.

Hundreds of different viruses cause cold symptoms, making a single cure extremely difficult to develop. It remains one of medicine's most familiar yet unsolved problems.

Despite decades of research, battery capacity has improved far more slowly than the power demands of our devices. A real breakthrough here would change how we use and design nearly all portable technology.

Despite recognition of its importance, reliable methods for teacher development platforms producing national-scale practice change are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for methods for reducing the transmission of antimicrobial resistance through food and environmental pathways are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for real-time systems for detecting and responding to food safety threats across supply chains are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for circular economy systems that eliminate leakage of plastics into the environment are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for institutional designs that reduce the influence of short-term interests on long-term policy are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for symbiont-mediated coral heat tolerance enhancement protocols are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for solutions for providing safe and dignified housing for climate-displaced populations are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for solutions for equitable access to high-quality secondary and tertiary education are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for solutions for managing the growing volumes of construction and demolition waste are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Stunting rates in parts of Mexico remain high despite food aid programs, because interventions rarely address the underlying combination of dietary diversity, sanitation, and maternal nutrition simultaneously.

Vocational training programs in Democratic Republic of Congo frequently teach skills misaligned with current employer demand, leaving graduates underemployed despite completing certification.

Despite recognition of its importance, reliable methods for protocols for responsible dual-use research in artificial intelligence and biotechnology are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for solutions for providing high-quality primary healthcare in remote and underserved regions are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for pathways for rapidly scaling regenerative agriculture without compromising yields are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for education systems that equip citizens to evaluate scientific claims in a high-misinformation environment are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.