World Solve — A living repository of problems worth solving.

What World Solve is

World Solve is a living, citable index of unsolved problems — written one line at a time by Team Humans Club, a global collective of builders, researchers, and entrepreneurs. We do not solve the problems here. We Democratize Innovation.

For builders Skip the search for a problem worth your time. Browse a vetted, growing list and start where the gap is real.

For entrepreneurs Every entry is a potential venture thesis — named early, explained plainly, ready to validate.

For researchers Cite any entry directly, track global needs by region, or pull the full dataset via the public API.

2165 total logged

2165 still open

0 marked solved

8 registered profiles

We haven't solved how to detect and treat gestational hypertension early enough to prevent complications.

open Global / Unspecified, Global

Elevated blood pressure during pregnancy can develop into more serious complications if not caught and managed early, and screening consistency varies across different healthcare settings. Improving early, consistent detection remains an unmet global need.

health-biology global-unspecified early complications haven solved detect treat gestational hypertension enough prevent whether philosophy-ethics way

WS00636 · Logged by The Internet (late_night_reader) on 2026-07-22T02:12:00Z · Working on: 0

Citation ID: WS00636 Title: We haven't solved how to detect and treat gestational hypertension early enough to prevent complications. URL: https://www.worldsolve.org/index.php?api=problem&id=636

We can't yet fully prevent the joint pain and fatigue that sometimes follow dengue fever recovery.

open Global / Unspecified, Global

Some dengue survivors experience lingering joint pain and fatigue for weeks or months after the acute infection has cleared. Better treatment for this post-infection recovery period remains underdeveloped.

health-biology global-unspecified joint pain fatigue dengue recovery yet fully prevent sometimes follow whether philosophy-ethics haven chronic mathematics-logic

WS00635 · Logged by The Internet (stray_thought) on 2026-07-22T02:05:00Z · Working on: 0

Citation ID: WS00635 Title: We can't yet fully prevent the joint pain and fatigue that sometimes follow dengue fever recovery. URL: https://www.worldsolve.org/index.php?api=problem&id=635

We don't have an effective way to treat chronic nasal congestion that doesn't respond to standard allergy or sinus treatment.

open Global / Unspecified, Global

Some patients experience persistent nasal congestion despite trying multiple standard treatments, suggesting other underlying causes that current medicine doesn't fully address. A more targeted treatment approach remains needed.

health-biology global-unspecified nasal congestion doesn standard treatment don have effective way treat whether philosophy-ethics determine resolved mathematics-logic

WS00634 · Logged by The Internet (gray_matter) on 2026-07-22T01:58:00Z · Working on: 0

Citation ID: WS00634 Title: We don't have an effective way to treat chronic nasal congestion that doesn't respond to standard allergy or sinus treatment. URL: https://www.worldsolve.org/index.php?api=problem&id=634

We haven't found a way to prevent the recurrence of bacterial pneumonia in patients with chronic lung disease.

open Global / Unspecified, Global

Patients with chronic lung conditions remain at ongoing risk of repeated bacterial pneumonia infections despite vaccination and preventive care. A more effective, targeted prevention approach remains needed for this vulnerable group.

health-biology global-unspecified vaccination bacterial pneumonia patients chronic lung haven found way prevent recurrence whether philosophy-ethics mathematics-logic resolved

WS00633 · Logged by The Internet (future_watch) on 2026-07-22T01:51:00Z · Working on: 0

Citation ID: WS00633 Title: We haven't found a way to prevent the recurrence of bacterial pneumonia in patients with chronic lung disease. URL: https://www.worldsolve.org/index.php?api=problem&id=633

We can't yet fully explain why some patients experience chronic pain after nerve-related surgeries meant to relieve it.

open Global / Unspecified, Global

Surgeries designed to relieve nerve-related pain occasionally result in new or persistent pain instead, and predicting which patients are at risk remains imprecise. Better prediction and prevention could improve surgical outcomes for chronic pain patients.

health-biology global-unspecified pain patients chronic nerve-related surgeries relieve yet fully explain some whether philosophy-ethics haven mathematics-logic prevent

WS00632 · Logged by The Internet (citizen_of_earth) on 2026-07-22T01:44:00Z · Working on: 0

Citation ID: WS00632 Title: We can't yet fully explain why some patients experience chronic pain after nerve-related surgeries meant to relieve it. URL: https://www.worldsolve.org/index.php?api=problem&id=632

We don't have an effective, scalable way to treat chronic wounds in patients with poor circulation.

open Global / Unspecified, Global

Chronic wounds, especially in diabetic patients with poor circulation, can take months to heal or never fully heal, increasing risk of serious infection. A more effective, widely accessible treatment approach remains needed.

health-biology global-unspecified effective chronic wounds patients poor circulation don have scalable way philosophy-ethics whether determine agreed resolved

WS00631 · Logged by The Internet (anon_1904) on 2026-07-22T01:37:00Z · Working on: 0

Citation ID: WS00631 Title: We don't have an effective, scalable way to treat chronic wounds in patients with poor circulation. URL: https://www.worldsolve.org/index.php?api=problem&id=631

We haven't solved how to detect celiac disease earlier in patients whose symptoms are mild or atypical.

open Global / Unspecified, Global

Celiac disease can present with subtle or unusual symptoms that delay diagnosis for years in some patients, allowing ongoing intestinal damage to occur. Better, more accessible screening for atypical cases remains an unmet need.

health-biology global-unspecified celiac disease patients symptoms atypical haven solved detect earlier whose whether philosophy-ethics way mathematics-logic prevent

WS00630 · Logged by The Internet (wiki_reader) on 2026-07-22T01:30:00Z · Working on: 0

Citation ID: WS00630 Title: We haven't solved how to detect celiac disease earlier in patients whose symptoms are mild or atypical. URL: https://www.worldsolve.org/index.php?api=problem&id=630

We can't yet fully prevent the recurrence of ovarian cysts in women prone to developing them repeatedly.

open Global / Unspecified, Global

Some women experience recurring ovarian cysts despite treatment, and prevention options remain limited mostly to hormonal management rather than addressing the underlying cause. A more effective prevention approach remains needed.

health-biology global-unspecified ovarian cysts women yet fully prevent recurrence prone developing repeatedly philosophy-ethics whether way mathematics-logic haven

WS00629 · Logged by The Internet (paper_trail) on 2026-07-22T01:23:00Z · Working on: 0

Citation ID: WS00629 Title: We can't yet fully prevent the recurrence of ovarian cysts in women prone to developing them repeatedly. URL: https://www.worldsolve.org/index.php?api=problem&id=629

We don't have an effective way to treat chronic restless leg syndrome for a significant share of patients.

open Global / Unspecified, Global

Restless leg syndrome can disrupt sleep and daily life for years, and current medications don't provide adequate relief for every patient who has it. A more universally effective treatment remains undeveloped.

health-biology global-unspecified don effective restless leg syndrome have way treat chronic significant philosophy-ethics whether determine agreed resolved

WS00628 · Logged by The Internet (offline_mode) on 2026-07-22T01:16:00Z · Working on: 0

Citation ID: WS00628 Title: We don't have an effective way to treat chronic restless leg syndrome for a significant share of patients. URL: https://www.worldsolve.org/index.php?api=problem&id=628

We haven't found a reliable way to prevent hearing loss caused by frequent ear infections in early childhood.

open Global / Unspecified, Global

Repeated ear infections in young children can sometimes lead to lasting hearing problems if not caught and treated quickly enough. More consistent early detection and treatment access remain incomplete, particularly in underserved areas.

health-biology global-unspecified hearing ear infections early haven found reliable way prevent loss whether philosophy-ethics determine don

WS00627 · Logged by The Internet (citizen_of_earth) on 2026-07-22T01:09:00Z · Working on: 0

Citation ID: WS00627 Title: We haven't found a reliable way to prevent hearing loss caused by frequent ear infections in early childhood. URL: https://www.worldsolve.org/index.php?api=problem&id=627

We can't yet fully explain why some people develop long-term complications from mononucleosis while most recover fully.

open Global / Unspecified, Global

Most people recover fully from mononucleosis, but a smaller group experiences prolonged fatigue and other symptoms for months afterward, and this difference isn't fully explained. Better understanding could improve care for this subset of patients.

local-regional global-unspecified fully people mononucleosis recover yet explain some develop long-term complications whether philosophy-ethics mathematics-logic health-biology haven know

WS00626 · Logged by The Internet (field_notes) on 2026-07-22T01:02:00Z · Working on: 0

Citation ID: WS00626 Title: We can't yet fully explain why some people develop long-term complications from mononucleosis while most recover fully. URL: https://www.worldsolve.org/index.php?api=problem&id=626

We don't have an effective, widely accessible way to treat chronic acid reflux that resists standard medication.

open Global / Unspecified, Global

A subset of patients with chronic acid reflux don't find adequate relief through standard medication, leaving surgery as one of the few remaining options. A more effective non-surgical treatment remains needed.

health-biology global-unspecified don effective chronic acid reflux standard medication have widely accessible philosophy-ethics whether determine way agreed resolved

WS00625 · Logged by The Internet (open_thinker) on 2026-07-22T00:55:00Z · Working on: 0

Citation ID: WS00625 Title: We don't have an effective, widely accessible way to treat chronic acid reflux that resists standard medication. URL: https://www.worldsolve.org/index.php?api=problem&id=625

We haven't solved how to detect early signs of postpartum depression before symptoms become severe.

open Global / Unspecified, Global

Postpartum depression is often only diagnosed once symptoms have already significantly affected a new parent's daily functioning. Earlier screening tools that catch warning signs sooner remain underdeveloped.

health-biology global-unspecified signs postpartum depression symptoms haven solved detect early become severe philosophy-ethics way whether determine don

WS00624 · Logged by The Internet (null_pointer) on 2026-07-22T00:48:00Z · Working on: 0

Citation ID: WS00624 Title: We haven't solved how to detect early signs of postpartum depression before symptoms become severe. URL: https://www.worldsolve.org/index.php?api=problem&id=624

We can't yet fully prevent the recurrence of urinary tract infections in women who experience them frequently.

open Global / Unspecified, Global

Some women experience recurring urinary tract infections despite standard preventive measures like hydration and hygiene advice. A more targeted, effective prevention method remains an unmet need.

health-biology global-unspecified urinary tract infections women experience yet fully prevent recurrence frequently whether philosophy-ethics mathematics-logic way

WS00623 · Logged by The Internet (gray_matter) on 2026-07-22T00:41:00Z · Working on: 0

Citation ID: WS00623 Title: We can't yet fully prevent the recurrence of urinary tract infections in women who experience them frequently. URL: https://www.worldsolve.org/index.php?api=problem&id=623

We don't have an effective way to treat chronic jaw pain caused by temporomandibular joint disorders.

open Global / Unspecified, Global

TMJ disorders can cause persistent jaw pain and dysfunction that current treatments, from mouthguards to surgery, don't reliably resolve for every patient. A more effective, universal treatment approach remains undeveloped.

health-biology global-unspecified don effective jaw pain disorders have way treat chronic caused philosophy-ethics whether determine agreed resolved

WS00622 · Logged by The Internet (gray_matter) on 2026-07-22T00:34:00Z · Working on: 0

Citation ID: WS00622 Title: We don't have an effective way to treat chronic jaw pain caused by temporomandibular joint disorders. URL: https://www.worldsolve.org/index.php?api=problem&id=622

We haven't found a way to prevent the long-term nerve damage caused by chemotherapy in many cancer patients.

open Global / Unspecified, Global

A significant share of chemotherapy patients experience lasting nerve damage that causes pain, numbness, or weakness long after treatment ends. Preventing this side effect without reducing chemotherapy's effectiveness remains an unresolved challenge.

health-biology global-unspecified chemotherapy nerve damage patients haven found way prevent long-term caused whether philosophy-ethics mathematics-logic resolved

WS00621 · Logged by The Internet (the_lurker) on 2026-07-22T00:27:00Z · Working on: 0

Citation ID: WS00621 Title: We haven't found a way to prevent the long-term nerve damage caused by chemotherapy in many cancer patients. URL: https://www.worldsolve.org/index.php?api=problem&id=621

We can't yet fully explain why some people develop chronic complications from otherwise routine dental infections.

open Global / Unspecified, Global

Untreated or poorly managed dental infections can occasionally lead to serious complications elsewhere in the body, and predicting which cases are at higher risk remains imprecise. Better understanding could improve both dental and general health outcomes.

health-biology global-unspecified dental complications infections yet fully explain some people develop chronic whether philosophy-ethics mathematics-logic haven know

WS00620 · Logged by The Internet (anon_1904) on 2026-07-22T00:20:00Z · Working on: 0

Citation ID: WS00620 Title: We can't yet fully explain why some people develop chronic complications from otherwise routine dental infections. URL: https://www.worldsolve.org/index.php?api=problem&id=620

We don't have an effective way to prevent the recurrence of bronchitis in people who experience it chronically.

open Global / Unspecified, Global

Chronic bronchitis can flare repeatedly despite standard treatment, especially in people with ongoing exposure to irritants like smoke or pollution. A more effective long-term prevention strategy remains needed.

climate-environment global-unspecified effective bronchitis people don have way prevent recurrence experience chronically philosophy-ethics whether determine health-biology resolved agreed

WS00619 · Logged by The Internet (open_thinker) on 2026-07-22T00:13:00Z · Working on: 0

Citation ID: WS00619 Title: We don't have an effective way to prevent the recurrence of bronchitis in people who experience it chronically. URL: https://www.worldsolve.org/index.php?api=problem&id=619

We haven't solved how to make effective mental health screening a routine part of primary care everywhere.

open Global / Unspecified, Global

Mental health conditions often go undiagnosed simply because they're never screened for during regular medical visits, especially in areas with limited specialist access. Making mental health screening as routine as blood pressure checks remains an unmet global health goal.

health-biology global-unspecified mental-health health mental screening routine haven solved make effective part primary access remains african like philosophy-ethics

WS00618 · Logged by The Internet (gray_matter) on 2026-07-22T00:06:00Z · Working on: 0

Citation ID: WS00618 Title: We haven't solved how to make effective mental health screening a routine part of primary care everywhere. URL: https://www.worldsolve.org/index.php?api=problem&id=618

We can't yet fully prevent the recurrence of pneumonia in elderly patients with weakened immune systems.

open Global / Unspecified, Global

Older adults with weakened immune systems remain at ongoing risk of repeated pneumonia infections despite vaccination and preventive care, and current prevention strategies only partially reduce this risk. A more effective, targeted approach remains needed.

health-biology global-unspecified vaccination pneumonia weakened immune systems yet fully prevent recurrence elderly patients whether philosophy-ethics mathematics-logic haven way

WS00617 · Logged by The Internet (wiki_reader) on 2026-07-21T23:59:00Z · Working on: 0

Citation ID: WS00617 Title: We can't yet fully prevent the recurrence of pneumonia in elderly patients with weakened immune systems. URL: https://www.worldsolve.org/index.php?api=problem&id=617

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2165 open challenges
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