World Solve

The absence of robust, context-adapted solutions for therapeutics and care models that improve outcomes for people living with multimorbidity creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

The absence of robust, context-adapted solutions for circular nutrient management systems closing phosphorus loops at regional scale creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Achieving methods for restoring the carbon sequestration capacity of terrestrial and coastal ecosystems at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Despite recognition of its importance, reliable methods for biotechnologies converting methane and CO2 into high-value chemicals and proteins are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

The absence of robust, context-adapted solutions for autonomous microgravity assembly of large habitats and infrastructure creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Current approaches to higher-order assessments valid under unrestricted AI tool access either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to methods for assessing the resilience of critical infrastructure to compound climate and cyber risks either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

The absence of robust, context-adapted solutions for governance models for ensuring the safety of advanced autonomous weapons systems creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

The absence of robust, context-adapted solutions for education systems that prepare students to navigate and shape the future of work with AI creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Achieving privacy-preserving detection of coordinated platform influence operations at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Achieving interventions that improve mental health and social cohesion in rapidly urbanizing populations at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Most households in Peru still cook with biomass fuels, driving deforestation and indoor air pollution, while clean cookstove adoption remains low due to upfront cost and unfamiliar cooking behavior.

Electronic waste volumes in Colombia are rising rapidly, but formal recycling capacity remains minimal, pushing most e-waste into informal, hazardous dismantling operations.

Current approaches to education systems that prepare citizens for active participation in democratic climate governance either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

The absence of robust, context-adapted solutions for psychological first-aid and mental health systems scalable after mass trauma creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Despite recognition of its importance, reliable methods for interventions that reduce the prevalence of non-communicable diseases through population-level action are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Millions of households in Fiji rely on borewells with naturally occurring fluoride or arsenic above safe thresholds, and current filtration technology is too costly or maintenance-intensive for rural deployment.

The absence of robust, context-adapted solutions for technologies enabling safe long-duration human presence beyond low Earth orbit creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Achieving self-sensing concrete reporting stress chloride and remaining life at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Current approaches to institutional innovations that increase the political durability of long-term climate policy either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.