We can't yet regenerate damaged heart tissue after a heart attack.
open
Global / Unspecified, Global
Heart muscle doesn't regenerate well once damaged, often leaving survivors with permanently reduced heart function. Finding a way to regrow healthy heart tissue could transform recovery for millions of survivors.
health-biology
global-unspecified
heart
regenerate
damaged
tissue
yet
attack
survivors
muscle
doesn
well
once
Citation ID: WS00216
Title: We can't yet regenerate damaged heart tissue after a heart attack.
URL: https://www.worldsolve.org/index.php?api=problem&id=216
We don't have an effective vaccine for most types of cancer.
open
Global / Unspecified, Global
Unlike infectious diseases, cancer arises from a person's own cells mutating, making a universal vaccine far more complex to design. Progress exists for a few cancer types, but a broadly effective approach remains unsolved.
health-biology
global-unspecified
infectious-disease
cancer
effective
vaccine
types
don
have
unlike
infectious
diseases
arises
philosophy-ethics
whether
determine
way
agreed
Citation ID: WS00215
Title: We don't have an effective vaccine for most types of cancer.
URL: https://www.worldsolve.org/index.php?api=problem&id=215
We haven't solved how to prevent light pollution from disrupting nocturnal wildlife in growing cities.
open
Global / Unspecified, Global
Artificial lighting confuses migration patterns, hunting behavior, and reproduction cycles in many nocturnal species, yet city lighting keeps expanding with growth. A widely adopted, wildlife-friendly lighting standard remains missing.
climate-environment
global-unspecified
nocturnal
lighting
haven
solved
prevent
light
pollution
disrupting
wildlife
growing
whether
philosophy-ethics
way
mathematics-logic
determine
agreed
Citation ID: WS00214
Title: We haven't solved how to prevent light pollution from disrupting nocturnal wildlife in growing cities.
URL: https://www.worldsolve.org/index.php?api=problem&id=214
We can't yet make air conditioning widely available in poorer, hot regions without worsening emissions.
open
Global / Unspecified, Global
Cooling saves lives during extreme heat, but most air conditioners rely on energy sources and refrigerants that contribute to climate change. A low-emission cooling solution accessible to poorer regions remains urgently needed.
climate-environment
global-unspecified
climate-change
air
poorer
regions
yet
make
conditioning
widely
available
hot
worsening
whether
haven
affordable
philosophy-ethics
mathematics-logic
Citation ID: WS00213
Title: We can't yet make air conditioning widely available in poorer, hot regions without worsening emissions.
URL: https://www.worldsolve.org/index.php?api=problem&id=213
We don't have a fair way to manage water rights between countries that share the same river.
open
Global / Unspecified, Global
Rivers often flow through multiple countries, and disputes over how much water each country can use remain a persistent source of tension. A widely accepted, fair sharing framework remains unbuilt in many major river basins.
climate-environment
global-unspecified
fair
water
countries
river
don
have
way
manage
rights
between
philosophy-ethics
whether
determine
agreed
resolved
haven
Citation ID: WS00212
Title: We don't have a fair way to manage water rights between countries that share the same river.
URL: https://www.worldsolve.org/index.php?api=problem&id=212
We haven't found an affordable way to retrofit old buildings to be energy efficient.
open
Global / Unspecified, Global
Older buildings often waste huge amounts of energy through poor insulation and outdated systems, but retrofitting them is usually expensive and disruptive. Cheaper retrofit solutions could unlock major emissions reductions from existing infrastructure.
climate-environment
global-unspecified
retrofit
buildings
energy
haven
found
affordable
way
old
efficient
older
whether
systems
mathematics-logic
philosophy-ethics
Citation ID: WS00211
Title: We haven't found an affordable way to retrofit old buildings to be energy efficient.
URL: https://www.worldsolve.org/index.php?api=problem&id=211
We can't yet stop soil erosion from steadily reducing farmland productivity worldwide.
open
Global / Unspecified, Global
Poor farming practices and deforestation are wearing away fertile topsoil faster than nature can rebuild it, threatening long-term food production. A scalable solution to reverse this trend remains unresolved globally.
climate-environment
global-unspecified
deforestation
yet
stop
soil
erosion
steadily
reducing
farmland
productivity
worldwide
poor
whether
philosophy-ethics
food
determine
prevent
Citation ID: WS00210
Title: We can't yet stop soil erosion from steadily reducing farmland productivity worldwide.
URL: https://www.worldsolve.org/index.php?api=problem&id=210
We don't have a reliable, affordable way to detect toxic algae blooms in water supplies before they become dangerous.
open
Global / Unspecified, Global
Algae blooms can quickly poison drinking water sources, sometimes going undetected until people or animals get sick. Faster, cheaper detection methods could prevent this from becoming a public health crisis.
health-biology
global-unspecified
public-health
algae
blooms
water
don
have
reliable
affordable
way
detect
toxic
philosophy-ethics
whether
determine
agreed
resolved
Citation ID: WS00209
Title: We don't have a reliable, affordable way to detect toxic algae blooms in water supplies before they become dangerous.
URL: https://www.worldsolve.org/index.php?api=problem&id=209
We haven't solved how to make electric vehicle batteries fully recyclable at the end of their life.
open
Global / Unspecified, Global
As electric vehicles become more common, so will the used batteries, most of which still lack an efficient, complete recycling process. Solving this prevents a looming new wave of battery waste.
climate-environment
global-unspecified
electric
batteries
haven
solved
make
vehicle
fully
recyclable
end
life
waste
recycling
systems
management
lacks
Citation ID: WS00208
Title: We haven't solved how to make electric vehicle batteries fully recyclable at the end of their life.
URL: https://www.worldsolve.org/index.php?api=problem&id=208
We can't yet stop illegal fishing from depleting fish stocks faster than regulations can respond.
open
Global / Unspecified, Global
Fishing fleets can evade detection in vast, poorly monitored ocean areas, undermining conservation efforts meant to protect fish populations. Better real-time monitoring at sea remains a critical unsolved gap.
society-governance
global-unspecified
fishing
fish
yet
stop
illegal
depleting
stocks
faster
regulations
respond
climate-environment
whether
populations
prevent
philosophy-ethics
mathematics-logic
Citation ID: WS00207
Title: We can't yet stop illegal fishing from depleting fish stocks faster than regulations can respond.
URL: https://www.worldsolve.org/index.php?api=problem&id=207
We don't have an efficient way to convert ocean wave energy into usable electricity at scale.
open
United States, North America
Wave energy is abundant and largely untapped, but current technology to harness it reliably and affordably lags far behind wind and solar. Cracking this could add a major renewable source to the global energy mix.
climate-environment
north-america
united-states
energy
wave
don
have
efficient
way
convert
ocean
usable
electricity
global-unspecified
whether
philosophy-ethics
determine
agreed
Citation ID: WS00206
Title: We don't have an efficient way to convert ocean wave energy into usable electricity at scale.
URL: https://www.worldsolve.org/index.php?api=problem&id=206
We haven't found a way to protect pollinator populations from the multiple threats they face at once.
open
Global / Unspecified, Global
Bees and other pollinators face combined pressure from pesticides, habitat loss, and disease, and addressing just one threat rarely solves the overall decline. A comprehensive solution addressing all major threats together remains unbuilt.
health-biology
global-unspecified
threats
face
haven
found
way
protect
pollinator
populations
multiple
once
whether
prevent
philosophy-ethics
climate-environment
mathematics-logic
loss
Citation ID: WS00205
Title: We haven't found a way to protect pollinator populations from the multiple threats they face at once.
URL: https://www.worldsolve.org/index.php?api=problem&id=205
We can't yet build packaging materials that decompose fully and safely without leaving microplastics behind.
open
Global / Unspecified, Global
Many products marketed as biodegradable still break down into tiny plastic particles that persist in the environment for years. A truly safe, fully compostable packaging material remains elusive at scale.
climate-environment
global-unspecified
packaging
fully
yet
build
materials
decompose
safely
leaving
microplastics
behind
mathematics-logic
whether
possible
haven
philosophy-ethics
know
Citation ID: WS00204
Title: We can't yet build packaging materials that decompose fully and safely without leaving microplastics behind.
URL: https://www.worldsolve.org/index.php?api=problem&id=204
We don't have cheap technology to capture and reuse water lost through evaporation in dry farming regions.
open
Global / Unspecified, Global
In hot, dry climates, a significant portion of irrigation water is lost to evaporation before it ever reaches crop roots. Affordable ways to reduce this loss could ease water stress in agriculture-heavy dry regions.
climate-environment
global-unspecified
water
dry
lost
evaporation
regions
don
have
cheap
technology
capture
philosophy-ethics
determine
urban
whether
long
Citation ID: WS00203
Title: We don't have cheap technology to capture and reuse water lost through evaporation in dry farming regions.
URL: https://www.worldsolve.org/index.php?api=problem&id=203
We haven't solved how to prevent groundwater contamination from industrial and agricultural runoff.
open
Global / Unspecified, Global
Chemicals and fertilizers seep into groundwater supplies over years, often going unnoticed until wells become unsafe to drink from. Preventing this contamination before it happens remains far harder than detecting it afterward.
local-regional
global-unspecified
groundwater
contamination
haven
solved
prevent
industrial
agricultural
runoff
chemicals
fertilizers
technology-computing
whether
climate-environment
mathematics-logic
fully
philosophy-ethics
Citation ID: WS00202
Title: We haven't solved how to prevent groundwater contamination from industrial and agricultural runoff.
URL: https://www.worldsolve.org/index.php?api=problem&id=202
We can't accurately measure how much carbon forests are really storing or losing in real time.
open
Global / Unspecified, Global
Estimates of forest carbon storage vary significantly depending on the measurement method used, making it hard to track progress on climate goals tied to reforestation. More precise, consistent measurement remains an open challenge.
climate-environment
global-unspecified
carbon
accurately
measure
forests
really
storing
losing
real
time
measurement
philosophy-ethics
whether
haven
way
resolved
don
Citation ID: WS00201
Title: We can't accurately measure how much carbon forests are really storing or losing in real time.
URL: https://www.worldsolve.org/index.php?api=problem&id=201
We don't have a reliable way to restore wetlands that have been destroyed by development.
open
Global / Unspecified, Global
Wetlands filter water and protect against flooding, but restoring one once it's been drained or built over is far harder than protecting it in the first place. Better restoration techniques remain limited and expensive.
climate-environment
global-unspecified
have
wetlands
been
don
reliable
way
restore
destroyed
development
filter
philosophy-ethics
whether
determine
agreed
resolved
Citation ID: WS00200
Title: We don't have a reliable way to restore wetlands that have been destroyed by development.
URL: https://www.worldsolve.org/index.php?api=problem&id=200
We haven't found a way to make solar panel production itself fully environmentally clean.
open
Global / Unspecified, Global
Manufacturing solar panels currently involves energy-intensive processes and some toxic materials, undercutting part of their environmental benefit. A cleaner production process would make solar energy's benefits more complete.
climate-environment
global-unspecified
solar
make
production
haven
found
way
panel
itself
fully
environmentally
mathematics-logic
whether
philosophy-ethics
Citation ID: WS00199
Title: We haven't found a way to make solar panel production itself fully environmentally clean.
URL: https://www.worldsolve.org/index.php?api=problem&id=199
We can't stop invasive species from spreading and damaging ecosystems faster than we can respond.
open
Global / Unspecified, Global
Non-native plants and animals often outcompete local species once introduced, and by the time damage is noticed, removal is difficult and expensive. Faster detection and response systems remain underdeveloped.
mathematics-logic
global-unspecified
species
faster
stop
invasive
spreading
damaging
ecosystems
respond
non-native
plants
philosophy-ethics
prevent
determine
harm
Citation ID: WS00198
Title: We can't stop invasive species from spreading and damaging ecosystems faster than we can respond.
URL: https://www.worldsolve.org/index.php?api=problem&id=198
We don't have widely available technology to convert agricultural waste into clean energy affordably.
open
United States, North America
Farms produce enormous amounts of leftover plant material that mostly gets burned or discarded rather than turned into usable energy. Affordable, small-scale conversion technology could turn this waste into a valuable resource.
climate-environment
north-america
united-states
technology
waste
energy
don
have
widely
available
convert
agricultural
clean
global-unspecified
philosophy-ethics
whether
determine
affordable
Citation ID: WS00197
Title: We don't have widely available technology to convert agricultural waste into clean energy affordably.
URL: https://www.worldsolve.org/index.php?api=problem&id=197