Repository of problems worth solving
World Solve is a public institutional repository for identifying real unresolved problems across science, society, health, governance, economics, and local systems. Each entry is intended to be citable, inspectable, and actionable.
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4194Total
4194Open
0Solved
9Humans
Despite recognition of its importance, reliable methods for therapies targeting the biology of multimorbidity rather than single diseases are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
health-biology
europe
sweden
therapies
targeting
biology
multimorbidity
rather
single
diseases
deployable
technologies
despite
climate-environment
methods
systems
barriers
society-governance
open
South Africa, Africa
Despite recognition of its importance, reliable methods for open standards for interoperable climate and biodiversity monitoring data are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
africa
south-africa
biodiversity
open
standards
interoperable
climate
monitoring
data
systemic
solutions
addressing
methods
systems
society-governance
technology-computing
barriers
Despite recognition of its importance, reliable methods for evidence frameworks for sequencing post-conflict institutional recovery are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
society-governance
asia
thailand
evidence
frameworks
sequencing
post-conflict
institutional
recovery
integrated
pathways
despite
recognition
climate-environment
methods
systems
barriers
designs
open
Mexico, North America
Despite recognition of its importance, reliable methods for technologies for selective removal of persistent organic pollutants from water bodies are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
north-america
mexico
methods
technologies
selective
removal
persistent
organic
pollutants
water
bodies
robust
society-governance
systems
enabling
barriers
designs
Despite recognition of its importance, reliable methods for biotechnologies enabling the production of pharmaceuticals and fine chemicals from renewable feedstocks are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
europe
poland
biotechnologies
enabling
production
pharmaceuticals
fine
chemicals
renewable
feedstocks
deployable
technologies
methods
systems
society-governance
barriers
high
Despite recognition of its importance, reliable methods for affordable methods for detecting and treating the major causes of childhood undernutrition are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
europe
netherlands
methods
affordable
detecting
treating
major
causes
childhood
undernutrition
field-ready
systems
society-governance
barriers
economics-resources
solutions
health-biology
open
Costa Rica, North America
Despite recognition of its importance, reliable methods for platform technologies for 30-day zoonotic antiviral response are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
north-america
costa-rica
platform
technologies
30-day
zoonotic
antiviral
response
scalable
solutions
despite
recognition
methods
systems
society-governance
barriers
designs
open
Chile, South America
Despite recognition of its importance, reliable methods for biotechnologies enabling the rapid development of vaccines against unknown future pathogens are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
health-biology
south-america
chile
biotechnologies
enabling
rapid
development
vaccines
against
unknown
future
pathogens
field-ready
climate-environment
systems
methods
society-governance
barriers
Despite recognition of its importance, reliable methods for governance models for managing the dual-use risks of advanced gene editing and synthetic biology are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
society-governance
africa
ethiopia
models
governance
managing
dual-use
risks
advanced
gene
editing
synthetic
biology
climate-environment
methods
systems
barriers
solutions
Despite recognition of its importance, reliable methods for methods for quantifying and reducing the climate impact of the global food system are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
europe
netherlands
methods
quantifying
reducing
climate
impact
food
system
robust
enabling
society-governance
systems
barriers
designs
solutions
assessing
Despite recognition of its importance, reliable methods for materials for efficient atmospheric water generation integrated with existing roofs are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
asia
japan
integrated
materials
efficient
atmospheric
water
generation
existing
roofs
pathways
despite
methods
systems
society-governance
barriers
designs
Despite recognition of its importance, reliable methods for governance frameworks for the responsible use of predictive policing and risk assessment tools are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
society-governance
asia
south-korea
governance
frameworks
responsible
predictive
policing
risk
assessment
tools
scalable
solutions
climate-environment
methods
systems
barriers
designs
open
Argentina, South America
Despite recognition of its importance, reliable methods for designs for energy storage that use only materials available in the Global South at scale are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
south-america
argentina
designs
energy
storage
only
materials
available
south
scale
development
methods
systems
society-governance
barriers
high
economics-resources
open
Brazil, South America
Despite recognition of its importance, reliable methods for quantum-resistant cryptography practical for constrained critical IoT are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
south-america
brazil
barriers
quantum-resistant
cryptography
practical
constrained
critical
iot
overcoming
despite
recognition
methods
systems
society-governance
designs
high
Despite recognition of its importance, reliable methods for biotechnologies for engineering organisms that contribute to the circular economy and waste reduction are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
economics-resources
oceania
fiji
barriers
biotechnologies
engineering
organisms
contribute
circular
economy
waste
reduction
overcoming
climate-environment
methods
systems
society-governance
high
Despite recognition of its importance, reliable methods for materials and designs for buildings that sequester carbon over their full life cycle are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
asia
nepal
materials
designs
buildings
sequester
carbon
over
full
life
cycle
breakthrough
methods
systems
barriers
society-governance
high
open
Costa Rica, North America
Despite recognition of its importance, reliable methods for ruminant microbiome interventions cutting methane over 50 percent are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
north-america
costa-rica
ruminant
microbiome
interventions
cutting
methane
over
percent
breakthrough
approaches
despite
methods
systems
barriers
society-governance
designs
open
Colombia, South America
Despite recognition of its importance, reliable methods for institutional designs that improve the accountability of international development and climate finance are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
south-america
colombia
institutional
designs
improve
accountability
international
development
climate
finance
practical
realization
society-governance
methods
systems
barriers
open
Mexico, North America
Despite recognition of its importance, reliable methods for designs for resilient food systems that maintain nutrition under multi-year drought are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
north-america
mexico
designs
resilient
food
systems
maintain
nutrition
under
multi-year
drought
scalable
society-governance
methods
solutions
economics-resources
barriers
Despite recognition of its importance, reliable methods for institutional arrangements that improve coordination across sectors for climate and SDG action are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.
climate-environment
europe
netherlands
institutional
arrangements
improve
coordination
sectors
climate
sdg
action
deployable
technologies
methods
society-governance
systems
designs
barriers