Healthcare equipment often uses sterile, complex, or regulated components that are difficult to reuse. Future systems need to reduce waste while preserving infection control and clinical reliability. Affected communities must have meaningful control over data, revenue, deployment decisions, and the right to refuse harmful applications. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
health-biology
circular
manufacturing
medical
devices
community
ownership
control
deployment
healthcare
equipment
technology-computing
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
open
Brazil, South America
People increasingly need trusted identity across migration, finance, education, health, and employment systems. The challenge is preventing fragmented credentials, exclusion, surveillance, and corporate dependency. Affected communities must have meaningful control over data, revenue, deployment decisions, and the right to refuse harmful applications. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
social-civic-problems
south-america
brazil
identity
public-interest
infrastructure
cross-border
digital
community
ownership
deployment
people
increasingly
technology-computing
economics-resources
climate-environment
systems
society-governance
open
Brazil, South America
No single model may cause harm when many models, sensors, contractors, and institutions interact. Legal systems need ways to assign responsibility across complex sociotechnical chains. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
south-america
brazil
accountability
decisions
made
distributed
machine
networks
low-income
communities
single
model
technology-computing
economics-resources
climate-environment
systems
infrastructure
Algorithmically designed foods may optimize cost, taste, shelf life, or emissions while neglecting long-term health and cultural acceptability. The challenge is creating transparent nutritional and ethical evaluation. Decisions must account for people who will inherit long-lived infrastructure, environmental changes, and institutional commitments. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
climate-environment
asia
india
foods
nutrition
standards
ai-designed
intergenerational
accountability
algorithmically
designed
may
optimize
technology-computing
economics-resources
society-governance
systems
infrastructure
Decision-makers lack integrated, high-resolution models of ocean chemistry, biology, currents, and human activity. The open problem is building trustworthy systems that support decisions without creating false confidence from incomplete data. The solution must produce useful coordination and accountability while minimizing collection of sensitive personal and behavioral data. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
europe
norway
real-time
marine
ecosystem
digital
twins
mass
surveillance
data
decision-makers
lack
society-governance
economics-resources
climate-environment
systems
without
Decision-makers lack integrated, high-resolution models of ocean chemistry, biology, currents, and human activity. The open problem is building trustworthy systems that support decisions without creating false confidence from incomplete data. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
europe
norway
real-time
marine
ecosystem
digital
twins
under
geopolitical
fragmentation
data
decision-makers
economics-resources
society-governance
systems
climate-environment
infrastructure
Decision-makers lack integrated, high-resolution models of ocean chemistry, biology, currents, and human activity. The open problem is building trustworthy systems that support decisions without creating false confidence from incomplete data. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
asia
philippines
real-time
marine
ecosystem
digital
twins
low-income
communities
decision-makers
lack
integrated
economics-resources
climate-environment
systems
society-governance
infrastructure
Growing desalination could produce concentrated brine and chemical waste at scales that threaten coastal ecosystems. The challenge is improving recovery and discharge methods while accounting for cumulative regional impacts. Decisions must account for people who will inherit long-lived infrastructure, environmental changes, and institutional commitments. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
europe
norway
desalination
brine
ocean
governance
intergenerational
accountability
growing
produce
concentrated
chemical
technology-computing
climate-environment
economics-resources
systems
infrastructure
Countries facing population decline may seek to influence reproductive decisions. The challenge is supporting people who want children, respecting those who do not, and addressing housing, work, care, and gender conditions rather than using coercive targets. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
family
policy
declining
fertility
coercion
low-income
communities
work
countries
facing
technology-computing
economics-resources
climate-environment
systems
infrastructure
quantum
science-space
Long-lived infrastructure and environmental decisions can impose costs on people who cannot vote today. The unresolved problem is creating legitimate institutions that represent future people without removing accountability from current citizens. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
climate-environment
future
political
representation
generations
low-income
communities
people
long-lived
infrastructure
environmental
technology-computing
economics-resources
society-governance
systems
quantum
science-space
safe
Interactive reconstructions of dead relatives may demand ongoing inclusion in gatherings, decisions, and emotional life. The problem is setting boundaries that respect both the living family’s autonomy and any residual rights or wishes of the deceased without forcing perpetual digital presence.
digital
deceased
family
life
managing
technology-computing
open
United States, North America
Autonomous spacecraft may make split-second avoidance decisions using imperfect data and proprietary software. The unresolved problem is assigning responsibility, proving fault, and compensating affected parties across jurisdictions. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
north-america
united-states
autonomous
spacecraft
liability
collisions
under
geopolitical
fragmentation
data
may
make
economics-resources
climate-environment
society-governance
systems
infrastructure
Autonomous spacecraft may make split-second avoidance decisions using imperfect data and proprietary software. The unresolved problem is assigning responsibility, proving fault, and compensating affected parties across jurisdictions. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
autonomous
spacecraft
liability
collisions
low-income
communities
may
make
split-second
avoidance
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
science-space
Severe solar storms can disrupt satellites, power grids, navigation, aviation, and communication networks. Future resilience requires better forecasting, hardened systems, coordinated shutdown procedures, and affordable protection for developing countries. Affected communities must have meaningful control over data, revenue, deployment decisions, and the right to refuse harmful applications. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
science-space
protection
space
weather
infrastructure
community
ownership
deployment
severe
solar
technology-computing
economics-resources
climate-environment
society-governance
systems
quantum
safe
without
AI-designed biological molecules may be created faster than their safety, ecological, and clinical properties can be characterized. The open problem is building evaluation pipelines proportionate to capability and deployment risk. Affected communities must have meaningful control over data, revenue, deployment decisions, and the right to refuse harmful applications. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
ai-designed
deployment
standards
proteins
community
ownership
biological
molecules
may
technology-computing
economics-resources
climate-environment
society-governance
systems
infrastructure
quantum
science-space
Digital consultation can produce large volumes of participation while still failing to influence decisions. The challenge is creating governance processes where consultation changes outcomes and does not become symbolic theater. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
consultation
informal
settlements
making
public
meaningful
scale
digital
produce
large
systems
technology-computing
across
climate-environment
institutions
Warnings often fail because people lack transport, trust, shelter, money, or authority to act. The unresolved problem is linking forecasts to pre-agreed decisions, resources, and responsibilities at local level. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
early
warning
systems
trigger
action
rather
only
alerts
low-income
communities
technology-computing
climate-environment
society-governance
infrastructure
quantum
social-civic-problems
science-space
Governments currently discount long-term harms because future people cannot vote today. The open problem is creating formal institutions that represent future citizens in budget, infrastructure, climate, and technology decisions. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
asia
bangladesh
future
informal
settlements
institutional
design
generations
representation
governments
currently
discount
systems
climate-environment
technology-computing
public
across
Future infrastructure will increasingly rely on systems capable of making decisions without immediate human supervision. The unresolved problem is creating architectures that can prove what they did, explain uncertainty, fail safely, and remain controllable during abnormal conditions. The solution must produce useful coordination and accountability while minimizing collection of sensitive personal and behavioral data. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
asia
india
infrastructure
auditable
autonomy
critical
mass
surveillance
future
will
increasingly
rely
society-governance
climate-environment
economics-resources
systems
without
Future infrastructure will increasingly rely on systems capable of making decisions without immediate human supervision. The unresolved problem is creating architectures that can prove what they did, explain uncertainty, fail safely, and remain controllable during abnormal conditions. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
asia
india
infrastructure
auditable
autonomy
critical
under
geopolitical
fragmentation
remain
future
will
technology-computing
society-governance
climate-environment
systems
quantum