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We haven't solved how to prevent the weight regain that follows most successful weight loss efforts.

open Global / Unspecified, Global WS00510
Even when people successfully lose significant weight, the body's biology often works to regain it over time, undermining long-term success. Understanding and countering this biological pushback remains a major open challenge.
Created at: 2026-07-21T11:30:00Z
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WS00510 | World Solve | https://www.worldsolve.org/index.php?view=problem&id=510

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