World Solve

Current approaches to point-of-care multiplex diagnostics for priority AMR pathogens either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to institutional arrangements that accelerate the diffusion of proven climate solutions either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to circular economy systems that eliminate leakage of plastics into the environment either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to interventions that reduce the transmission of vector-borne diseases under changing climate either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

A persistent gap exists in realizing practical, scalable solutions for solutions for providing reliable and affordable internet access in rural and remote regions. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for affordable methods for the early detection and treatment of the major cancers in LMICs. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

Current approaches to methods for restoring soil biodiversity and function after intensive conventional agriculture either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to methods for restoring the ecological function of rivers fragmented by dams and infrastructure either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to technologies enabling precise monitoring of greenhouse gas emissions from individual facilities either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

A persistent gap exists in realizing practical, scalable solutions for architectural innovations that make high-performance buildings affordable for low-income households. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for real-time monitoring systems for tracking the recovery of ecosystems after restoration interventions. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

Current approaches to institutional designs that improve the effectiveness of multi-level climate governance either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to technologies for the safe and efficient recycling of advanced battery chemistries either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Current approaches to solutions for providing reliable and affordable energy access in displacement and refugee settings either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

A persistent gap exists in realizing practical, scalable solutions for governance of dual-use research that balances scientific freedom and catastrophic risk reduction. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for galactic cosmic ray shielding without prohibitive mass penalties. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for microbiome restoration after repeated antibiotic exposure in children. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for governance frameworks for managing the risks and opportunities of advanced human enhancement. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

Current approaches to governance frameworks for managing the dual-use risks of advanced computing and AI technologies either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

A persistent gap exists in realizing practical, scalable solutions for supply chain transparency systems that verifiably exclude forced and child labor. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.