Engineered microbes, insects, crops, and gene drives may offer major ecological benefits but could spread beyond intended boundaries. The unresolved problem is developing reversible, monitorable, and internationally governed release frameworks. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
release
engineered
safe
environmental
organisms
low-income
communities
microbes
insects
crops
technology-computing
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
Biological design tools are becoming more accessible while oversight remains fragmented across countries and institutions. The challenge is detecting dangerous activity without suppressing legitimate research or creating an intrusive global surveillance system. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
asia
india
monitoring
synthetic
biology
risk
under
geopolitical
fragmentation
design
research
technology-computing
economics-resources
society-governance
climate-environment
systems
infrastructure
Biological design tools are becoming more accessible while oversight remains fragmented across countries and institutions. The challenge is detecting dangerous activity without suppressing legitimate research or creating an intrusive global surveillance system. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
monitoring
synthetic
biology
risk
low-income
communities
research
biological
design
technology-computing
economics-resources
climate-environment
society-governance
systems
quantum
infrastructure
science-space
Future societies may need shared datasets for health, mobility, climate, education, and infrastructure. The challenge is creating commons rules that enable useful access while preventing extraction, surveillance, and inequitable control. The challenge is especially acute for low-resource administrations, where legacy systems, coordination failures, and weak oversight can magnify harm.
climate-environment
commons
low-resource
administrations
governance
public
data
future
societies
may
need
society-governance
systems
technology-computing
across
without
climate
low
open
South Africa, Africa
Future societies may need shared datasets for health, mobility, climate, education, and infrastructure. The challenge is creating commons rules that enable useful access while preventing extraction, surveillance, and inequitable control. The challenge is especially acute without mass surveillance, where legacy systems, coordination failures, and weak oversight can magnify harm.
climate-environment
africa
south-africa
surveillance
commons
mass
governance
public
data
future
societies
may
need
society-governance
systems
technology-computing
without
across
open
Mexico, North America
Future societies may need shared datasets for health, mobility, climate, education, and infrastructure. The challenge is creating commons rules that enable useful access while preventing extraction, surveillance, and inequitable control. The challenge is especially acute in post-conflict institutions, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
north-america
mexico
commons
post-conflict
institutions
governance
public
data
future
societies
may
need
systems
climate-environment
technology-computing
across
without
Future societies may need shared datasets for health, mobility, climate, education, and infrastructure. The challenge is creating commons rules that enable useful access while preventing extraction, surveillance, and inequitable control. The challenge is especially acute across fragmented municipalities, where legacy systems, coordination failures, and weak oversight can magnify harm.
climate-environment
africa
kenya
commons
fragmented
municipalities
governance
public
data
future
societies
may
need
society-governance
systems
technology-computing
across
without
Warnings often fail because people lack transport, trust, shelter, money, or authority to act. The unresolved problem is linking forecasts to pre-agreed decisions, resources, and responsibilities at local level. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
early
warning
systems
trigger
action
rather
only
alerts
low-income
communities
technology-computing
climate-environment
society-governance
infrastructure
quantum
social-civic-problems
science-space
A seawall, air conditioner, reservoir, or drought-resistant crop can reduce one risk while increasing inequality, heat, debt, ecological damage, or downstream exposure. The challenge is evaluating full-system consequences before large investments are locked in. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
climate-environment
protecting
climate
adaptation
projects
maladaptation
low-income
communities
seawall
air
conditioner
technology-computing
economics-resources
society-governance
systems
quantum
infrastructure
science-space
Drought, salinization, erosion, and heat may displace people gradually rather than through one visible disaster. The open problem is creating legal pathways, funding mechanisms, and host-community planning before displacement becomes coercive. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
climate-environment
displacement
climate
migration
agreements
slow-onset
low-income
communities
drought
salinization
erosion
technology-computing
economics-resources
society-governance
systems
quantum
infrastructure
science-space
Many agricultural and infrastructure systems are designed around historical seasons that may no longer exist. A useful solution must help governments revise calendars, reservoirs, insurance, crops, and public budgets under deep uncertainty. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
africa
kenya
planning
permanent
changes
seasonal
rainfall
low-income
communities
solution
must
agricultural
technology-computing
economics-resources
climate-environment
systems
infrastructure
Future cities may experience extreme heat precisely when electricity and water systems are least able to support cooling. The challenge is coordinating urban design, demand management, public health, and energy policy under compound stress. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
climate-environment
public-health
water-scarcity
cities
heat
water
climate
adaptation
simultaneous
scarcity
low-income
communities
future
technology-computing
economics-resources
systems
society-governance
infrastructure
Public systems using legacy cryptography will eventually face long-term exposure as quantum computers improve. The challenge is coordinating migration across ministries, vendors, archives, and critical infrastructure without breaking public services. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
asia
indonesia
systems
migration
informal
settlements
governance
post-quantum
state
public
legacy
cryptography
technology-computing
climate-environment
across
Large quantum computers may require specialized materials, cooling systems, and high-energy facilities. Their lifecycle impact, component reuse, and end-of-life management are not yet adequately designed. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
asia
japan
reuse
quantum
safe
disposal
cryogenic
hardware
low-income
communities
large
computers
economics-resources
climate-environment
society-governance
systems
infrastructure
Claims about quantum advantage often depend on narrow benchmarks or idealized assumptions. The challenge is creating reproducible measurements that identify when quantum systems deliver meaningful benefits over classical alternatives. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
quantum
benchmarking
algorithms
against
societal
needs
low-income
communities
identify
claims
economics-resources
climate-environment
society-governance
systems
infrastructure
science-space
safe
Future quantum networks will need coexistence with conventional fiber, satellites, and noisy metropolitan infrastructure. A major unresolved problem is developing practical repeaters, interfaces, standards, and operational security for real-world deployment. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
science-space
asia
japan
quantum
infrastructure
networking
over
ordinary
telecommunications
low-income
communities
deployment
future
technology-computing
economics-resources
climate-environment
society-governance
systems
Quantum capabilities could transform optimization, chemistry, intelligence, and cryptanalysis while becoming concentrated in a few states. The challenge is preventing destabilizing secrecy and unequal access without blocking peaceful scientific collaboration. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
asia
india
quantum
international
governance
advantage
under
geopolitical
fragmentation
access
capabilities
transform
technology-computing
economics-resources
climate-environment
systems
infrastructure
Quantum capabilities could transform optimization, chemistry, intelligence, and cryptanalysis while becoming concentrated in a few states. The challenge is preventing destabilizing secrecy and unequal access without blocking peaceful scientific collaboration. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
quantum
international
governance
advantage
low-income
communities
capabilities
transform
optimization
chemistry
technology-computing
economics-resources
climate-environment
systems
infrastructure
science-space
safe
Quantum sensors may detect hidden water, minerals, leaks, tunnels, and structural anomalies, but their cost, calibration, and interpretation remain barriers. The open problem is converting laboratory sensitivity into dependable field services. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
asia
japan
quantum
deployment
sensor
underground
infrastructure
low-income
communities
services
sensors
may
technology-computing
climate-environment
society-governance
systems
science-space
Private companies may increasingly run water, transport, energy, communication, and housing systems with public consequences. The open problem is designing regulation that ensures reliability, accountability, and public recourse when essential services fail. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
africa
nigeria
private
informal
settlements
governance
high-risk
infrastructure
operators
systems
public
companies
technology-computing
climate-environment
across
climate