Repository of problems worth solving
World Solve is a public institutional repository for identifying real unresolved problems across science, society, health, governance, economics, and local systems. Each entry is intended to be citable, inspectable, and actionable.
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4194Total
4194Open
0Solved
9Humans
open
Global / Unspecified, Global
Cell and gene therapies may deliver durable remissions but have complex safety profiles. Post-marketing registries and patient-reported outcome platforms can close knowledge gaps.
climate-environment
global-unspecified
therapies
new
cancer
will
demand
better
real-world
data
understand
long-term
society-governance
public
registries
health-biology
governance
technology-computing
open
Global / Unspecified, Global
Cell and gene therapies may deliver durable remissions but have complex safety profiles. Post-marketing registries and patient-reported outcome platforms can close knowledge gaps.
climate-environment
global-unspecified
data
therapies
new
cancer
will
demand
better
real-world
understand
long-term
society-governance
technology-computing
infrastructure
african
systems
europe
open
Global / Unspecified, Global
Even advanced AI systems can confidently state things that violate obvious physical logic, like objects falling upward or liquids not filling containers. This gap shows current AI still lacks a genuine model of how the physical world works.
mathematics-logic
global-unspecified
physical
build
models
reason
reliably
basic
common
sense
even
advanced
philosophy-ethics
whether
haven
resolved
systems
know
open
United States, North America
Kepler and other missions have identified thousands of exoplanets, but we lack robust statistics on Earth-size worlds with stable climates and liquid water. Next-generation transit and direct-imaging missions must refine occurrence rates.
climate-environment
north-america
united-states
not
know
common
truly
earth-like
habitable
planets
missions
kepler
global-unspecified
whether
philosophy-ethics
science-space
don
determine
open
Global / Unspecified, Global
Moons like Europa and Enceladus may harbor oceans beneath ice, but we do not know their chemical gradients or energy sources. Cryobot and plume-sampling missions could test for conditions suitable for life.
climate-environment
global-unspecified
lack
precise
constraints
habitability
subsurface
ocean
worlds
moons
like
europa
know
philosophy-ethics
whether
mathematics-logic
don
determine
open
Global / Unspecified, Global
Depression and anxiety are leading causes of disability but receive little funding and few providers in most countries. Teletherapy and lay-counselor models can expand coverage.
health-biology
global-unspecified
mental-health
mental
health
services
remain
severely
under-resourced
worldwide
depression
anxiety
leading
access
remains
whether
african
society-governance
Drug-resistant TB strains are spreading faster than diagnostic capacity in India, Pakistan, and Bangladesh. Portable AI-assisted chest X-ray screening and better contact-tracing apps could catch cases earlier.
health-biology
asia
india
tuberculosis
diagnostic-capacity
south
carries
world
highest
burdens
drug-resistant
strains
spreading
treatment
global-unspecified
migrant
workers
way
Cities like Manila, Jakarta, and Mumbai rank among the world's most congested, costing billions in lost time and fuel. Integrated mass-transit expansion and smart traffic-management systems are urgently needed.
economics-resources
asia
traffic
congestion
asian
megacities
causes
massive
economic
productivity
losses
cities
african
systems
urban
global-unspecified
climate-environment
infrastructure
Viral misinformation has fueled real-world violence and health misinformation in several countries with weak media literacy programs. Fact-checking tools integrated directly into popular messaging apps could slow its spread.
social-civic-problems
asia
misinformation
media
messaging
apps
spreads
rapidly
social
viral
has
global-unspecified
whether
philosophy-ethics
remains
african
access
society-governance
Palm oil and timber industries clear forest at rates that threaten orangutans and other endangered species while releasing significant carbon emissions. Sustainable palm oil certification and satellite-based deforestation tracking need stronger enforcement.
climate-environment
asia
indonesia
deforestation
carbon-emissions
threaten
malaysia
continues
some
world
biodiverse
rainforests
palm
global-unspecified
philosophy-ethics
way
have
whether
open
Sub-Saharan Africa, Africa
Stockouts of antiretrovirals are common due to weak logistics and donor dependency. Local manufacturing and predictive supply-chain software could reduce treatment interruptions.
technology-computing
africa
sub-saharan-africa
supply-chain
carries
world
hiv
burden
but
drug
supply
chains
remain
global-unspecified
economics-resources
african
whether
health-biology
Import dependency and poor local production capacity make fertilizer unaffordable for most smallholders. Local phosphate and nitrogen production ventures could sharply cut costs.
economics-resources
africa
fertilizer
prices
among
highest
world
relative
income
local
production
global-unspecified
society-governance
african
remains
climate-environment
affordable
access
Over 90 million children are not enrolled in school, driven by poverty, conflict, and distance to schools. Low-cost offline-capable e-learning tablets could reach remote learners cheaply.
economics-resources
africa
children
has
world
highest
rate
out-of-school
over
million
not
social-civic-problems
global-unspecified
education
low
school
remain
asia
Most households and farms have no protection against disasters, illness, or crop failure, deepening poverty cycles. Micro-insurance products bundled with mobile money could expand coverage rapidly.
economics-resources
africa
insurance
penetration
among
lowest
world
households
farms
have
protection
products
climate-environment
climate
global-unspecified
against
shocks
african
High data costs limit access to online education, jobs, and business tools for lower-income users. Local infrastructure investment and spectrum-sharing policies could bring prices down.
economics-resources
africa
mobile
internet
remains
among
expensive
relative
income
worldwide
high
global-unspecified
african
technology-computing
whether
access
infrastructure
philosophy-ethics
open
Global / Unspecified, Global
Because operators on Earth must check every step, rovers cover only meters per day on distant worlds. Fully autonomous, vision-guided AI navigation system operating locally on edge hardware is needed.
science-space
global-unspecified
rovers
robotic
planetary
move
far
too
slowly
over
unfamiliar
terrain
autonomous
lack
systems
algorithms
decentralized
satellite
open
Global / Unspecified, Global
Collecting samples from Venus or deep Martian canyons requires multi-stage rockets launching autonomously from foreign surfaces. Lightweight planetary ascent vehicles and automated orbital rendezvous systems must be built.
science-space
global-unspecified
systems
planetary
lack
autonomous
sample
return
missions
high-gravity
worlds
collecting
society-governance
technology-computing
climate-environment
economics-resources
ensuring
public
open
Global / Unspecified, Global
The 1967 Outer Space Treaty is ambiguous regarding commercial resource extraction and private property. Clear, enforceable international frameworks are needed to encourage private investment in off-world mining.
science-space
global-unspecified
private
mining
property
there
standardized
legal
framework
asteroid
rights
orbital
society-governance
governance
whether
philosophy-ethics
technology-computing
public
open
Global / Unspecified, Global
Constellations operating near distant worlds cannot rely on continuous control from Earth operators. Distributed mesh networks and collision-avoidance algorithms operating autonomously across dozens of nodes must be developed.
science-space
global-unspecified
algorithms
lack
autonomous
decentralized
satellite
swarm
coordination
deep
space
operating
illegal
unreported
fishing
waters
near
planetary
open
Global / Unspecified, Global
SETI surveys are flooded with terrestrial radio interference, making it difficult to detect faint off-world signals. Edge AI signal processing algorithms trained to filter human RF noise in real time must be deployed.
technology-computing
global-unspecified
radio
search
technosignatures
alien
optical
transmissions
lacks
standardized
real-time
filtering
internal
displacement
tracking
responding
philosophy-ethics
whether