Edible products that trigger audio or sensory ads when chewed create unavoidable commercial intrusion into a basic biological act. The problem is protecting the privacy and dignity of eating while still permitting voluntary information delivery for those who want it.
eliminating
built
advertisements
activate
during
mathematics-logic
When corporations patent forms of rainwater collection or composition in water-scarce areas, ordinary puddles and runoff become potential infringement sites. The challenge is designing water-rights frameworks that protect both innovation incentives and the basic human need for free access to precipitation.
rainwater
resolving
legal
ownership
conflicts
climate-environment
Climate events, cyberattacks, and conflict can demand action faster than standard legislative processes allow. The open problem is creating emergency authorities with strong checks, expiration rules, and public review. This becomes particularly difficult in informal settlements, because public institutions must remain fair, resilient, and accountable while adapting to new risks.
climate-environment
africa
nigeria
institutions
informal
settlements
designing
democratic
high-speed
crisis
response
public
climate
society-governance
governance
high
Cities may deploy scent systems that automatically adjust collective emotional states. Over time some residents develop tolerance or adverse reactions, creating uneven effects and new forms of environmental inequality. The problem is designing transparent, opt-outable, and medically safe atmospheric interventions that do not become tools of coercion or social control.
scent
managing
public
emitters
alter
health-biology
When personal memory archives exist solely in distributed cloud systems, sudden or gradual data loss can erase formative experiences without local backups. The challenge is building durable, verifiable, and accessible long-term personal memory infrastructure that survives corporate failure, format obsolescence, and account lapses. Solutions should remain affordable, user-controlled, and recoverable even decades later.
cloud
systems
ensuring
childhood
memories
other
open
Mexico, North America
As identity, payments, records, and service portals become central to state capacity, failures will produce large-scale disputes. The unresolved problem is setting up fast, fair, and trusted systems to resolve them. This becomes particularly difficult in informal settlements, because public institutions must remain fair, resilient, and accountable while adapting to new risks.
society-governance
north-america
mexico
state-capacity
institutions
public
informal
settlements
creating
dispute
resolution
digital
infrastructure
fair
systems
technology-computing
governance
Future governments will need near-real-time visibility into commitments, arrears, off-budget liabilities, and contingent risks. The open problem is building financial transparency systems that ordinary citizens and auditors can actually use. This becomes particularly difficult in informal settlements, because public institutions must remain fair, resilient, and accountable while adapting to new risks.
society-governance
asia
bangladesh
public
informal
settlements
making
finance
legible
real
time
risks
future
institutions
systems
climate-environment
governance
As more government activity moves online, corruption may shift from visible cash handling to invisible data manipulation, access control, and procurement capture. The challenge is detecting abuse in systems that look efficient on the surface. This becomes particularly difficult in informal settlements, because public institutions must remain fair, resilient, and accountable while adapting to new risks.
society-governance
resilient
systems
informal
settlements
creating
anti-corruption
digital
states
government
activity
public
technology-computing
institutions
across
corruption
Public services will increasingly depend on rapidly updated models and decision pipelines. The unresolved problem is keeping these systems lawful, understandable, and corrigible as they evolve faster than formal regulations. This becomes particularly difficult in informal settlements, because public institutions must remain fair, resilient, and accountable while adapting to new risks.
society-governance
africa
nigeria
public
services
informal
settlements
designing
adaptable
governance
emerging
will
increasingly
systems
institutions
technology-computing
Some future climate interventions may have planetary effects while remaining scientifically and politically contested. The challenge is designing governance for experimentation, consent, liability, and termination before deployment escalates. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
climate-environment
climate
informal
settlements
regulating
engineering
under
deep
uncertainty
some
future
society-governance
systems
technology-computing
public
across
governance
AI-designed biological molecules may be created faster than their safety, ecological, and clinical properties can be characterized. The open problem is building evaluation pipelines proportionate to capability and deployment risk. The approach must scale before formal institutions, infrastructure, and land-use systems fully catch up with population growth. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
asia
india
ai-designed
standards
proteins
rapidly
urbanizing
regions
deployment
approach
biological
technology-computing
society-governance
economics-resources
climate-environment
systems
infrastructure
Biometric identity can reduce fraud while also excluding people whose fingerprints, faces, or documents do not match. The open problem is creating identity governance that is secure without making access to basic entitlements brittle. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
africa
nigeria
biometric
systems
informal
settlements
controlling
misuse
verification
welfare
identity
reduce
technology-computing
public
across
climate-environment
without
open
Brazil, South America
Genomic medicine could improve treatment while enabling insurers, employers, states, or platforms to infer sensitive traits. The challenge is ensuring people benefit from precision medicine without losing control over biological information. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
south-america
brazil
medicine
personalized
genetic
discrimination
low-income
communities
genomic
improve
treatment
while
economics-resources
climate-environment
society-governance
systems
quantum
open
Mexico, North America
Historical records increasingly exist in fragile digital formats that may outlive current software, vendors, and hardware. The unresolved problem is preserving public memory across decades of technological change. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
technology-computing
north-america
mexico
public
digital
informal
settlements
protection
archives
against
extinction
historical
records
society-governance
systems
across
institutions
climate-environment
open
Brazil, South America
AI agents may perform tasks once done by contractors, analysts, translators, and assistants. The challenge is creating rules for liability, taxation, attribution, and market fairness when human labor and machine labor overlap. The challenge is especially acute across multiple jurisdictions, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
south-america
brazil
labor
multiple
jurisdictions
governance
synthetic
markets
agents
may
perform
tasks
across
systems
technology-computing
climate-environment
public
AI agents may perform tasks once done by contractors, analysts, translators, and assistants. The challenge is creating rules for liability, taxation, attribution, and market fairness when human labor and machine labor overlap. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
europe
germany
labor
informal
settlements
governance
synthetic
markets
agents
may
perform
tasks
systems
technology-computing
climate-environment
public
across
open
Brazil, South America
Future outbreaks may involve pathogens for which no profitable commercial market exists. A useful solution requires distributed manufacturing, adaptable platforms, pre-negotiated procurement, and equitable access before an outbreak occurs. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
south-america
brazil
manufacturing
pathogens
market
rapid
vaccine
existing
low-income
communities
solution
future
technology-computing
climate-environment
society-governance
systems
quantum
Predictive policing can reinforce historical bias even when built from apparently neutral data. The open problem is designing standards that make public safety tools testable, reviewable, and defeasible when they cause harm. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
asia
bangladesh
predictive
policing
informal
settlements
independent
audits
government
harm
reinforce
historical
systems
public
technology-computing
across
climate-environment
Digital consultation can produce large volumes of participation while still failing to influence decisions. The challenge is creating governance processes where consultation changes outcomes and does not become symbolic theater. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
society-governance
consultation
informal
settlements
making
public
meaningful
scale
digital
produce
large
systems
technology-computing
across
climate-environment
institutions
Border systems may increasingly use risk scoring, biometric checks, and predictive screening. The unresolved problem is ensuring security tools do not become opaque instruments of arbitrary exclusion or rights violations. The challenge is especially acute in informal settlements, where legacy systems, coordination failures, and weak oversight can magnify harm.
health-biology
africa
nigeria
systems
exclusion
border
informal
settlements
preventing
automated
migration
may
increasingly
society-governance
technology-computing
public
climate-environment
across