Repository of problems worth solving
World Solve is a public institutional repository for identifying real unresolved problems across science, society, health, governance, economics, and local systems. Each entry is intended to be citable, inspectable, and actionable.
Publicly citable
Every problem has a stable citation code for reference and discussion.
Filtered by relevance
Search by category, geography, status, and keywords.
Builder-oriented
Use the repository to find startup ideas, policy leads, and research agendas.
4194Total
4194Open
0Solved
9Humans
open
Global / Unspecified, Global
Persistent symptoms after infections strain health systems and productivity, yet mechanisms are incompletely understood. Large longitudinal cohorts and mechanistic studies are needed to inform care pathways.
health-biology
global-unspecified
long
covid
post-viral
syndromes
may
remain
significant
burden
2030s
persistent
systems
society-governance
health
whether
public
data
open
Global / Unspecified, Global
Persistent symptoms after infections strain health systems and productivity, yet mechanisms are incompletely understood. Large longitudinal cohorts and mechanistic studies are needed to inform care pathways.
health-biology
global-unspecified
long
covid
post-viral
syndromes
may
remain
significant
burden
2030s
variant
data
society-governance
systems
economics-resources
will
health
open
Global / Unspecified, Global
Cell and gene therapies may deliver durable remissions but have complex safety profiles. Post-marketing registries and patient-reported outcome platforms can close knowledge gaps.
climate-environment
global-unspecified
data
therapies
new
cancer
will
demand
better
real-world
understand
long-term
society-governance
technology-computing
infrastructure
african
systems
europe
open
Global / Unspecified, Global
By 2040, many patients will have multiple chronic conditions with overlapping treatments and risks. Care orchestration tools and polypharmacy-optimisation systems are needed.
society-governance
global-unspecified
will
multi-morbidity
become
norm
older
adults
2040
patients
have
multiple
systems
health-biology
public
philosophy-ethics
whether
mathematics-logic
open
Global / Unspecified, Global
Pervasive digital platforms may exacerbate sleep, focus, and mood problems. New prevention strategies, digital hygiene tools, and regulatory frameworks will be needed.
technology-computing
global-unspecified
digital
will
mental-health
infrastructure
struggle
keep
pace
rising
addiction
society-governance
african
systems
public
low
institutions
open
Global / Unspecified, Global
Advances in synthetic biology may blur the line between accidental and deliberate outbreaks. Genomic anomaly detection and secure reporting pipelines could help.
society-governance
global-unspecified
bio-surveillance
systems
will
need
detect
engineered
threats
well
natural
health-biology
philosophy-ethics
detection
distributed
economics-resources
ensuring
outbreak
open
Global / Unspecified, Global
Poor-quality medicines accelerate resistance and treatment failure. Track-and-trace systems and quality-testing infrastructure are needed.
health-biology
global-unspecified
resistance
antimicrobial
low-resource
settings
will
exacerbated
counterfeit
substandard
drugs
poor-quality
systems
society-governance
climate-environment
infrastructure
technology-computing
economics-resources
open
Antarctica / Unspecified, Antarctica
Rising temperatures and changing winds are destabilising ice shelves and altering Southern Ocean circulation, with global implications for sea-level rise and extreme weather. High-resolution coupled climate–ice models and sustained observation networks are needed to predict these changes.
climate-environment
antarctica
antarctica-unspecified
climate-change
ice
climate
ocean
change
rapidly
transforming
systems
rising
temperatures
under
migration
global-unspecified
society-governance
methods
open
Antarctica / Unspecified, Antarctica
Penguin, krill, and seabird populations are already shifting or declining as habitats change and food webs reorganise. Long-term ecological monitoring and ecosystem-modelling platforms are needed to guide conservation.
mathematics-logic
antarctica
antarctica-unspecified
antarctic
ecosystems
face
emerging
threats
warming
acidification
changing
sea
ice
climate-environment
global-unspecified
prevent
philosophy-ethics
whether
open
Antarctica / Unspecified, Antarctica
Antarctic waters absorb large fractions of excess heat and CO2, yet models disagree on future behaviour and feedbacks. Expanded biogeochemical observing systems and process studies can refine global climate models.
climate-environment
antarctica
antarctica-unspecified
heat
southern
ocean
role
carbon
uptake
poorly
constrained
models
antarctic
systems
society-governance
climate
global-unspecified
whether
open
Antarctica / Unspecified, Antarctica
More ships and visitors increase risks of pollution, wildlife disturbance, and accidents in fragile environments. Data-driven tourism management systems and binding guidelines could reduce impact.
climate-environment
antarctica
antarctica-unspecified
tourism
antarctic
growing
fully
tested
sustainability
safety
standards
ships
visitors
systems
society-governance
ensuring
global-unspecified
mathematics-logic
open
Antarctica / Unspecified, Antarctica
Demand for krill-based products and fish drives fleets into sensitive ecosystems that underpin Antarctic food webs. Improved stock assessment and real-time monitoring platforms can inform precautionary management.
society-governance
antarctica
antarctica-unspecified
fisheries
southern
ocean
including
krill
risk
overexploitation
demand
krill-based
products
climate-environment
global-unspecified
economics-resources
mathematics-logic
systems
open
Antarctica / Unspecified, Antarctica
Shifts in global power, resource interest, and security concerns challenge consensus-based environmental governance. Scenario-analysis and compliance-monitoring tools can help strengthen the regime.
society-governance
antarctica
antarctica-unspecified
governance
under
antarctic
treaty
system
faces
new
geopolitical
pressures
shifts
frameworks
models
use
ensuring
systems
open
Antarctica / Unspecified, Antarctica
Science, tourism, and fishing activities leave infrastructure, pollution, and disturbance, but their combined effects are under-studied. Spatial-impact mapping and cumulative-effects assessment platforms are needed.
technology-computing
antarctica
antarctica-unspecified
lack
comprehensive
data
human
footprint
cumulative
impacts
science
tourism
climate-environment
global-unspecified
society-governance
african
infrastructure
systems
open
Antarctica / Unspecified, Antarctica
Emerging evidence suggests shifts in Antarctic hydrological cycles that affect ice-mass balance and ecosystems. Enhanced meteorological observations and models can clarify trends.
mathematics-logic
antarctica
antarctica-unspecified
extreme
precipitation
events
changing
snowfall
patterns
poorly
understood
emerging
evidence
society-governance
real
time
systems
open
Antarctica / Unspecified, Antarctica
Supply chains for fuel, food, and equipment depend on limited routes and budgets, constraining long-term research. Optimisation tools and shared logistics platforms could improve resilience.
economics-resources
antarctica
antarctica-unspecified
supply-chain
logistical
support
antarctic
science
vulnerable
cost
weather
geopolitical
shocks
supply
global-unspecified
climate-environment
african
systems
open
Antarctica / Unspecified, Antarctica
Antarctic systems underpin climate regulation and biodiversity, but their economic and non-market value is rarely quantified. Valuation tools and decision-support models could elevate their importance in policy.
climate-environment
antarctica
antarctica-unspecified
biodiversity
value
lack
robust
frameworks
assessing
ecosystem
services
antarctic
systems
society-governance
methods
climate
global-unspecified
whether
open
Antarctica / Unspecified, Antarctica
Research, tourism, and fishing generate emissions and local effects that are not fully tracked or integrated into global accounting. Standardised carbon-footprint and mitigation-planning tools are needed.
climate-environment
antarctica
antarctica-unspecified
cumulative
climate
impact
activities
under-measured
variant
focuses
data
monitoring
global-unspecified
society-governance
african
europe
systems
technology-computing
open
Antarctica / Unspecified, Antarctica
Access to field programmes is often restricted to well-funded institutions from certain countries. Virtual research infrastructures and inclusive collaboration models could broaden participation.
society-governance
antarctica
antarctica-unspecified
research
participation
remote
harsh
conditions
limit
inclusivity
diversity
antarctic
access
global-unspecified
mathematics-logic
systems
philosophy-ethics
whether
open
Antarctica / Unspecified, Antarctica
Warming may alter soil stability, hydrology, and microbial activity, affecting infrastructure and ecosystems. Long-term ground-temperature networks and modelling tools can track changes.
climate-environment
antarctica
antarctica-unspecified
changes
permafrost
active-layer
antarctic
soils
not
fully
monitored
warming
may
mathematics-logic
whether
global-unspecified
philosophy-ethics
society-governance
