World Solve

Design care models that maintain treatment continuity for migrants, truck drivers, seasonal workers, and displaced people who routinely cross administrative boundaries.

Build transparent testing, traceability, and regulatory methods for identifying heavy metals, steroids, pharmaceuticals, and contaminants in traditional medicine supply chains.

Develop scalable rehabilitation systems that combine community workers, telemedicine, low-cost devices, and culturally appropriate exercises for stroke survivors far from specialists.

Determine how heat, dehydration, pesticide exposure, and labor conditions interact to cause chronic kidney disease, then build practical prevention systems for agricultural and construction workers.

Develop surveillance and affordable safety protocols for dialysis delivered in fragmented private and informal systems, where contamination and equipment reuse may go undocumented.

Create field-deployable chemical verification methods that pharmacies, regulators, and patients can use to distinguish authentic cancer drugs from counterfeit or degraded products.

Achieving early warning systems for social unrest linked to climate and resource stress at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Governments and households in disaster-prone regions of India lack pre-arranged financing mechanisms, forcing reliance on slow post-disaster aid appeals rather than rapid, budgeted recovery funds.

Achieving systems ensuring the safety and reliability of AI systems used in critical infrastructure control at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Flash floods in Australia frequently strike with too little warning for effective evacuation, because rainfall and river-level monitoring networks remain too sparse to model localized risk accurately.

Despite recognition of its importance, reliable methods for safe and effective methods for large-scale insect protein production and use are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Despite recognition of its importance, reliable methods for passive cooling and ventilation systems for informal settlement housing are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Informal-sector workers in Yemen are largely excluded from formal credit because they lack the documented income history traditional lenders require, forcing reliance on high-interest informal lenders.

Children displaced from Yemen frequently experience multi-year gaps in schooling because host communities lack accredited pathways to integrate them into local education systems.

Achieving early childhood development programs proven effective at national scale under fiscal constraint at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Achieving methods for restoring the carbon sequestration capacity of terrestrial and coastal ecosystems at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Utilities and hospitals in Democratic Republic of Congo increasingly face ransomware attacks, but many operate on legacy systems without the budget or expertise to implement modern cybersecurity defenses.

Vietnam sits along a known wildlife trafficking corridor, and enforcement agencies lack the forensic and tracking tools needed to intercept shipments and prosecute organized trafficking networks effectively.

Achieving privacy-preserving detection of coordinated platform influence operations at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Achieving interventions that improve mental health and social cohesion in rapidly urbanizing populations at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.