Repository of problems worth solving
World Solve is a public institutional repository for identifying real unresolved problems across science, society, health, governance, economics, and local systems. Each entry is intended to be citable, inspectable, and actionable.
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4194Total
4194Open
0Solved
9Humans
open
Global / Unspecified, Global
This disfiguring and disabling condition continues to affect millions in tropical regions, and while some treatments exist, access remains inconsistent and the underlying infection prevention needs further improvement. Closing this gap remains an ongoing global health priority.
health-biology
global-unspecified
remains
regions
haven
found
effective
affordable
way
treat
elephantiasis
all
whether
philosophy-ethics
mathematics-logic
resolved
determine
don
open
Global / Unspecified, Global
Resistant malaria strains have emerged in certain regions and are gradually spreading, threatening to undermine decades of progress against the disease. Coordinated, faster response to contain resistance before it spreads further remains incomplete.
health-biology
global-unspecified
malaria
haven
solved
prevent
spread
drug-resistant
parasites
borders
resistant
strains
whether
philosophy-ethics
way
mathematics-logic
resolved
determine
open
Global / Unspecified, Global
Complications during childbirth can become fatal within minutes without access to emergency care, and many regions still lack the infrastructure to respond quickly enough. Closing this gap remains one of the most urgent unmet needs in global health.
health-biology
global-unspecified
regions
access
emergency
care
don
have
scalable
way
reduce
maternal
whether
philosophy-ethics
determine
resolved
agreed
open
Global / Unspecified, Global
Current malaria prevention still depends heavily on physical barriers and insecticides, both of which face growing resistance and logistical challenges in the regions most affected. A more durable prevention method remains an urgent unmet need.
health-biology
global-unspecified
malaria
haven
found
widely
available
way
prevent
transmission
relying
primarily
whether
philosophy-ethics
mathematics-logic
resolved
determine
open
Global / Unspecified, Global
Many parts of the world have extremely few mental health professionals relative to their population, leaving most people with mental health needs entirely unsupported. Solving this requires new models of care delivery, not just more funding.
health-biology
global-unspecified
mental-health
mental
health
have
professionals
don
scalable
way
provide
support
regions
whether
philosophy-ethics
determine
resolved
open
Global / Unspecified, Global
Hospitals with limited resources for sterile equipment and infection control see higher rates of post-surgical infections than better-equipped facilities. Closing this gap requires both medical and infrastructure solutions that remain incomplete in many regions.
health-biology
global-unspecified
infections
haven
solved
prevent
surgical
site
resource-limited
hospital
settings
hospitals
whether
philosophy-ethics
solutions
society-governance
way
mathematics-logic
open
Global / Unspecified, Global
Chronic malnutrition in early childhood can cause lasting physical and cognitive effects that are difficult to reverse later in life. Preventing this before it happens remains far more effective, and far less solved, than treating it afterward.
health-biology
global-unspecified
solved
haven
prevent
malnutrition-related
stunting
children
food-insecure
regions
far
chronic
whether
philosophy-ethics
way
mathematics-logic
determine
open
Global / Unspecified, Global
Stomach cancer often causes no clear symptoms until it has progressed significantly, particularly in regions without routine screening programs. Earlier, more accessible detection could substantially improve survival outcomes.
health-biology
global-unspecified
stomach
cancer
haven
found
reliable
way
detect
early-stage
becomes
advanced
whether
philosophy-ethics
determine
resolved
don
open
Global / Unspecified, Global
Infections like Zika or cytomegalovirus can cause serious birth defects if contracted during pregnancy, and prevention options remain limited in many regions. Better vaccines or protective treatments remain needed to close this gap.
health-biology
global-unspecified
birth
defects
infections
during
pregnancy
yet
fully
prevent
caused
certain
philosophy-ethics
whether
haven
way
mathematics-logic
open
Global / Unspecified, Global
This parasitic disease affects millions in tropical and subtropical regions, but effective treatment remains expensive, difficult to access, or logistically challenging for many affected communities. Closing this access gap remains unresolved.
health-biology
global-unspecified
regions
don
have
affordable
cure
leishmaniasis
available
all
endemic
remains
whether
philosophy-ethics
determine
way
resolved
agreed
open
Global / Unspecified, Global
Malnutrition rates spike dramatically in areas affected by war, but delivering treatment consistently in unstable, hard-to-reach regions remains a persistent logistical and medical challenge. Solving this requires both medical and access innovation.
health-biology
global-unspecified
malnutrition
access
don
have
scalable
solution
treating
conflict
zones
aid
whether
philosophy-ethics
determine
way
resolved
agreed
open
Global / Unspecified, Global
Cervical cancer remains highly preventable through regular screening, but many women in lower-resource regions lack consistent access to the tests that catch it early. Closing this access gap could prevent large numbers of otherwise preventable deaths.
health-biology
global-unspecified
access
cervical
cancer
regions
regular
don
have
scalable
way
screen
whether
philosophy-ethics
determine
resolved
agreed
open
Global / Unspecified, Global
Effective treatments for hepatitis B exist, but cost and access remain out of reach for many of the hundreds of millions of people living with the infection globally, particularly in lower-income regions. Closing this access gap remains unresolved.
health-biology
global-unspecified
hepatitis
don
have
scalable
affordable
treatment
available
everyone
infected
worldwide
whether
philosophy-ethics
determine
way
resolved
agreed
open
Global / Unspecified, Global
Drug-resistant tuberculosis requires longer, more expensive, and more toxic treatment regimens that many patients in affected regions simply can't access or complete. This keeps a preventable disease deadly in the parts of the world least equipped to fight it.
health-biology
global-unspecified
tuberculosis
treatment
don
have
affordable
widely
available
strains
resistant
standard
whether
philosophy-ethics
way
determine
resolved
agreed
open
Global / Unspecified, Global
Severe bleeding after childbirth remains one of the leading causes of maternal death worldwide, disproportionately in regions lacking access to blood transfusions and advanced medical care. Affordable, effective solutions for these settings remain limited.
health-biology
global-unspecified
settings
haven
solved
treat
postpartum
hemorrhage
effectively
low-resource
severe
bleeding
philosophy-ethics
whether
affordable
way
determine
solutions
open
Global / Unspecified, Global
As some regions become less livable due to heat, drought, or flooding, governments often lack a clear, proactive plan for how internal migration should be managed. This leaves affected communities dealing with sudden, poorly supported relocation.
climate-environment
global-unspecified
migration
government
responses
climate
own
borders
remain
largely
unplanned
reactive
under
society-governance
pressure
african
relocation
systems
open
Global / Unspecified, Global
Population shifts toward cities or away from certain regions can leave old district boundaries badly mismatched with current populations, distorting how fairly votes translate into representation. Regularly updating these boundaries fairly remains politically contentious.
local-regional
global-unspecified
political
districts
drawn
decades
ago
sometimes
longer
reflect
people
actually
philosophy-ethics
whether
representation
have
determine
society-governance
open
Global / Unspecified, Global
Fewer reporters are left covering city councils, local courts, and regional agencies, meaning much of everyday governance now happens with almost no public scrutiny. This local news gap makes accountability at the community level far harder to maintain.
society-governance
global-unspecified
local
news
coverage
government
activity
has
collapsed
regions
traditional
media
economics-resources
recovery
african
africa
remains
conflict
open
Global / Unspecified, Global
During emergencies, confusion over which agency is responsible for what can delay critical decisions when speed matters most. Clearer, pre-agreed emergency governance structures remain inconsistently established across different regions.
society-governance
global-unspecified
government
responses
disasters
frequently
slowed
unclear
lines
authority
between
agencies
whether
philosophy-ethics
governance
health-biology
public
african
open
Global / Unspecified, Global
As populations shift toward cities, rural areas can be left with proportionally less political power even though they still depend heavily on government services like roads and healthcare access. Balancing this representation gap remains an unresolved tension in many democracies.
society-governance
global-unspecified
rural
less
political
representation
regions
countries
have
far
relative
needs
whether
philosophy-ethics
access
determine
way
resolved