World Solve

The absence of robust, context-adapted solutions for interventions that reliably improve mental health outcomes at population scale creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

The absence of robust, context-adapted solutions for protocols for the rapid and ethical evaluation of new medical and public health interventions creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Informal settlements in Yemen largely rely on pit latrines with no formal desludging service, leading to overflow into waterways and elevated diarrheal disease rates among children.

Women remain significantly underrepresented in STEM higher education and careers in South Africa, a gap that begins with unequal encouragement and resources at the secondary school level.

Current approaches to methods for quantifying the full environmental and social costs of different energy pathways either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

Despite recognition of its importance, reliable methods for scalable methods for restoring peatland hydrology and carbon stocks are still lacking. Progress is hindered by incomplete mechanistic knowledge, high capital and operational barriers, and the absence of deployment models suited to the contexts of greatest need.

Current approaches to architectural and planning approaches that make cities more equitable and climate-resilient simultaneously either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

A persistent gap exists in realizing practical, scalable solutions for institutional designs that make long-term climate and sustainability policy more durable across political cycles. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

Achieving technologies for safe and efficient long-distance transport of hydrogen and ammonia at meaningful scale demands simultaneous progress in fundamental research, engineering integration and socio-technical systems that work for low- and middle-income settings. Existing efforts remain fragmented relative to the magnitude of the challenge.

Current approaches to technologies enabling efficient and low-impact desalination and water treatment at various scales either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

A persistent gap exists in realizing practical, scalable solutions for pathways for integrating traditional ecological knowledge with modern environmental management. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

Rapid urban growth in Indonesia has produced large informal settlements lacking basic infrastructure, and in-place upgrading approaches remain rare compared to displacement-driven redevelopment models.

The absence of robust, context-adapted solutions for scalable interventions improving executive function after chronic stress creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

The absence of robust, context-adapted solutions for governance frameworks for the ethical development and deployment of human enhancement technologies creates cascading risks across interconnected human and natural systems. Key missing elements include durable performance, low lifetime cost, and governance arrangements capable of sustaining impact beyond pilot stages.

Current approaches to biotechnologies enabling the production of high-value materials from captured carbon dioxide either underperform under variable field conditions or generate externalities that undermine long-term sustainability and equity. Closing the gap requires coordinated advances in science, systems design and enabling institutions.

A persistent gap exists in realizing practical, scalable solutions for governance models for ensuring the safety of advanced AI systems capable of recursive self-improvement. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for methods for reducing the environmental footprint of the global healthcare system. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for predictive analytics for anticipating and preventing cascading infrastructure failures. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for affordable and durable solutions for the management of household and industrial organic waste. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for ethical and technical frameworks for human-AI collaboration in high-stakes decision making. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.