Repository of problems worth solving
World Solve is a public institutional repository for identifying real unresolved problems across science, society, health, governance, economics, and local systems. Each entry is intended to be citable, inspectable, and actionable.
Publicly citable
Every problem has a stable citation code for reference and discussion.
Filtered by relevance
Search by category, geography, status, and keywords.
Builder-oriented
Use the repository to find startup ideas, policy leads, and research agendas.
4194Total
4194Open
0Solved
9Humans
open
Global / Unspecified, Global
Mental health conditions often go undiagnosed simply because they're never screened for during regular medical visits, especially in areas with limited specialist access. Making mental health screening as routine as blood pressure checks remains an unmet global health goal.
health-biology
global-unspecified
mental-health
health
mental
screening
routine
haven
solved
make
effective
part
primary
whether
philosophy-ethics
society-governance
access
remains
open
Global / Unspecified, Global
Older adults with weakened immune systems remain at ongoing risk of repeated pneumonia infections despite vaccination and preventive care, and current prevention strategies only partially reduce this risk. A more effective, targeted approach remains needed.
health-biology
global-unspecified
vaccination
pneumonia
weakened
immune
systems
yet
fully
prevent
recurrence
elderly
patients
whether
philosophy-ethics
mathematics-logic
haven
resolved
open
Global / Unspecified, Global
Some children experience repeated seizures triggered by fever, and current prevention strategies remain limited mostly to managing fever itself rather than addressing the underlying seizure susceptibility. A more effective prevention approach remains needed.
health-biology
global-unspecified
seizures
children
haven
found
reliable
way
prevent
recurrence
febrile
young
whether
philosophy-ethics
determine
resolved
mathematics-logic
open
Global / Unspecified, Global
Recurrent bacterial vaginosis affects a meaningful share of women despite standard treatment, suggesting current approaches don't fully address the underlying imbalance causing it. A more effective long-term prevention method remains needed.
philosophy-ethics
global-unspecified
fully
bacterial
vaginosis
women
yet
prevent
recurrence
experience
chronically
recurrent
whether
health-biology
mathematics-logic
way
resolved
haven
open
Global / Unspecified, Global
Some patients experience persistent fatigue for months after major surgery that goes beyond typical recovery time, and the reasons for this aren't fully understood. Better prevention and treatment of post-surgical fatigue remains an underexplored area.
health-biology
global-unspecified
fatigue
major
surgery
don
have
effective
way
prevent
chronic
sometimes
philosophy-ethics
whether
resolved
determine
agreed
open
Global / Unspecified, Global
This disfiguring and disabling condition continues to affect millions in tropical regions, and while some treatments exist, access remains inconsistent and the underlying infection prevention needs further improvement. Closing this gap remains an ongoing global health priority.
health-biology
global-unspecified
remains
regions
haven
found
effective
affordable
way
treat
elephantiasis
all
whether
philosophy-ethics
mathematics-logic
resolved
determine
don
open
Global / Unspecified, Global
High blood pressure can silently damage the kidneys over years before any symptoms appear, and by the time damage is detected, it's often already significant. Earlier, more sensitive detection methods remain an unmet need.
health-biology
global-unspecified
damage
high
blood
pressure
don
have
reliable
way
detect
early
philosophy-ethics
whether
determine
resolved
agreed
open
Global / Unspecified, Global
Extended antibiotic use can disrupt gut bacteria in ways that cause lasting digestive problems for some patients, even after the antibiotics are no longer needed. Better protection of the gut microbiome during necessary antibiotic treatment remains undeveloped.
health-biology
global-unspecified
antibiotic
digestive
yet
fully
prevent
sometimes
follow
long-term
gut
extended
whether
philosophy-ethics
mathematics-logic
haven
resolved
open
Global / Unspecified, Global
Standard gestational diabetes screening often happens later in pregnancy and can be logistically difficult to access in under-resourced areas, delaying diagnosis and management. Earlier, more accessible screening remains an unmet need.
health-biology
global-unspecified
gestational
diabetes
earlier
pregnancy
don
have
effective
scalable
way
detect
philosophy-ethics
whether
determine
resolved
agreed
open
Global / Unspecified, Global
A subset of patients develop long-lasting pain after surgeries that are usually uncomplicated for most people, and the biological reason for this difference isn't fully understood. Better prediction and prevention could reduce this often overlooked outcome.
mathematics-logic
global-unspecified
fully
people
develop
pain
haven
found
way
explain
some
chronic
whether
philosophy-ethics
health-biology
resolved
determine
open
Global / Unspecified, Global
Hormone-related migraines can be particularly difficult to prevent using standard migraine treatments, leaving affected patients with limited effective options. A more targeted prevention approach remains needed.
health-biology
global-unspecified
prevent
migraines
patients
yet
fully
recurrence
triggered
hormonal
changes
some
whether
philosophy-ethics
way
mathematics-logic
haven
resolved
open
Global / Unspecified, Global
While uncommon, some patients experience hiccups that persist for weeks or longer, disrupting sleep, eating, and daily life, and effective treatment options remain limited. A more reliable treatment approach for these rare cases remains undeveloped.
health-biology
global-unspecified
effective
hiccups
persist
rare
cases
don
have
way
treat
chronic
philosophy-ethics
whether
determine
resolved
agreed
open
Global / Unspecified, Global
Even when Lyme disease is caught and treated early, a portion of patients still develop lasting symptoms, and doctors don't fully understand why treatment doesn't fully resolve the illness in every case. Solving this could improve outcomes for a currently underserved group of patients.
health-biology
global-unspecified
fully
patients
develop
lyme
disease
early
treatment
yet
explain
some
philosophy-ethics
whether
mathematics-logic
haven
resolved
way
open
Global / Unspecified, Global
Hair loss after childbirth is common and usually temporary, but effective treatments to speed recovery or reduce severity remain limited. While not medically dangerous, better options could ease a common and distressing postpartum experience.
health-biology
global-unspecified
effective
postpartum
hair
loss
don
have
widely
accessible
way
treat
whether
philosophy-ethics
determine
resolved
agreed
open
Global / Unspecified, Global
Long-term use of some widely available pain medications can gradually damage kidney function, often without obvious symptoms until damage is significant. Better awareness and prevention methods remain incompletely applied.
health-biology
global-unspecified
damage
long-term
kidney
pain
medications
haven
solved
prevent
caused
certain
whether
philosophy-ethics
way
mathematics-logic
resolved
determine
open
Global / Unspecified, Global
Chronic fatigue syndrome is diagnosed in women considerably more often than men, and the biological or social reasons behind this imbalance remain only partly understood. A clearer answer could improve diagnosis and treatment for both sexes.
mathematics-logic
global-unspecified
chronic
fatigue
syndrome
women
men
yet
fully
explain
affects
frequently
whether
philosophy-ethics
health-biology
haven
resolved
open
Global / Unspecified, Global
Persistent dizziness linked to inner ear problems can be difficult to diagnose precisely and treat effectively, leaving many patients with ongoing symptoms. A more reliable, targeted treatment approach remains undeveloped.
health-biology
global-unspecified
treat
dizziness
inner
ear
patients
haven
found
effective
way
chronic
whether
philosophy-ethics
determine
resolved
mathematics-logic
don
open
Global / Unspecified, Global
Some patients experience ongoing digestive issues after gallbladder removal, a very common surgery, and current understanding of why this happens in some but not others remains incomplete. Better prevention or treatment of these complications remains needed.
health-biology
global-unspecified
digestive
complications
gallbladder
removal
surgery
yet
fully
prevent
follow
some
whether
philosophy-ethics
mathematics-logic
haven
resolved
way
open
Global / Unspecified, Global
Many children with obesity go on to develop related health issues as adults, and current interventions haven't proven consistently effective at reversing childhood obesity at a population scale. A more effective, scalable approach remains an urgent unmet need.
health-biology
global-unspecified
effective
obesity
scalable
childhood
related
don
have
way
treat
leads
philosophy-ethics
whether
determine
resolved
agreed
open
Global / Unspecified, Global
Resistant malaria strains have emerged in certain regions and are gradually spreading, threatening to undermine decades of progress against the disease. Coordinated, faster response to contain resistance before it spreads further remains incomplete.
health-biology
global-unspecified
malaria
haven
solved
prevent
spread
drug-resistant
parasites
borders
resistant
strains
whether
philosophy-ethics
way
mathematics-logic
resolved
determine
