World Solve

Build locally actionable models of how warming, rainfall, urbanization, immunity, and mobility reshape mosquito- and tick-borne disease risks.

Develop accessible multidimensional diagnostics and treatments for chronic pain that reduce reliance on addictive medications while avoiding dismissal of patient suffering.

Establish reliable exposure measurement, causal evidence, biological mechanisms, and practical interventions for microplastics in food, water, and air.

Develop independent methods to measure when ranking algorithms intensify ethnic, religious, electoral, or communal tension in specific regional contexts.

A persistent gap exists in realizing practical, scalable solutions for distributed methane leak detection and auto-mitigation systems. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for education and training systems that prepare populations for climate-driven livelihood transitions. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for mechanisms for ensuring that the benefits of the bioeconomy are shared with biodiversity-rich countries. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for real-time systems for detecting and responding to the illegal trade in timber and forest products. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for real-time attribution of extreme weather events to climate change for adaptation planning. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for technologies for the continuous monitoring and verification of methane emissions from multiple sectors. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for affordable methods for the continuous monitoring of environmental and occupational health hazards. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for therapeutics that reverse or halt the progression of major neurodegenerative diseases. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for systems ensuring the safety and reliability of autonomous vehicles in mixed traffic environments. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for early detection of groundwater depletion and quality decline at basin scale. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for biotechnologies for engineering organisms that produce high-value compounds from CO2 and renewable energy. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for pathways for achieving universal access to clean and reliable electricity by 2030. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for real-time systems for detecting and responding to the emergence of novel zoonotic diseases. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for passive architectural cooling effective above 30 C wet-bulb. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for technologies enabling precise monitoring of soil health and carbon stocks at farm and landscape scales. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.

A persistent gap exists in realizing practical, scalable solutions for institutional designs that reduce the risk of nuclear escalation in multipolar crises. Scientific understanding, engineering readiness and institutional capacity remain insufficient to translate promising concepts into durable impact under real-world constraints of cost, skills and governance.