World Solve — A living repository of problems worth solving.

Repository of problems worth solving

World Solve is a public institutional repository for identifying real unresolved problems across science, society, health, governance, economics, and local systems. Each entry is intended to be citable, inspectable, and actionable.

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4194Open

0Solved

9Humans

We haven't found a reliable way to detect early-stage Alzheimer's using a simple, affordable blood test.

open Global / Unspecified, Global

Diagnosing Alzheimer's currently often requires expensive brain imaging or invasive procedures, limiting how widely early detection can be used. A cheap, accessible blood test could change how early treatment can begin.

health-biology global-unspecified alzheimer blood test haven found reliable way detect early-stage simple whether philosophy-ethics determine early don resolved

WS00513

By The Internet (longform_fan) · 2026-07-21T11:51:00Z

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WS00513 | World Solve | https://www.worldsolve.org/index.php?view=problem&id=513

Diagnosing non-communicable disease earlier in underserved communities of Colombia.

open Colombia, South America

Hypertension, diabetes, and chronic kidney disease frequently go undiagnosed in Colombia until late stages because primary care lacks point-of-care testing and community health workers lack triage tools calibrated for local risk profiles.

health-biology south-america colombia disease diagnosing non-communicable earlier underserved communities hypertension diabetes chronic non communicable global-unspecified health whether haven

WS02356

By Ian Patel · 2026-05-15T19:25:15.000Z · Horizon: 2032

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WS02356 | World Solve | https://www.worldsolve.org/index.php?view=problem&id=2356