World Solve

intersex children facing non-consensual surgery remains one of the most urgent challenges of our time. Systems currently in place are inadequate for the scale and complexity of the problem. A successful approach must work where resources are scarcest and demonstrate clear, measurable results. It should identify possible harms, respect local agency, and show how the solution can be maintained and expanded by the communities it is meant to serve.

Over the next two decades, rising resistance in bacteria, fungi, and parasites risks undermining surgery, chemotherapy, and intensive care. Global surveillance networks, rapid diagnostics, and new antimicrobial development platforms are crucial to avert a post-antibiotic era.

Ageing populations, urban diets, and pollution will drive surges in cardiovascular disease, diabetes, cancer, and chronic respiratory conditions. Scalable chronic-care models, digital coaching tools, and preventive policy reforms are needed.

Major urban centres like Berlin, Paris, and Barcelona face rent and home price surges that outpace incomes. Policy-simulation platforms and modular construction ventures could inform and implement solutions.

Aging infrastructure and demand surges cause frequent power outages that disrupt businesses and daily life. Localized battery-backed microgrids could provide more resilient power in outage-prone regions.

Groups like Boko Haram and al-Shabaab exploit weak governance and poverty to recruit and control territory. Community-resilience programs paired with local economic opportunity have shown more success than military approaches alone.

In major agricultural and industrial manufacturing regions across East and South Asia, overuse of antibiotics in livestock and unmonitored factory discharge have accelerated the proliferation of drug-resistant pathogens, threatening global healthcare systems.

Bridges, ports, and power stations across island nations are built with conventional standards that fail during combined seismic events, storm surges, and landslides, cutting off entire island populations from emergency relief.

Decades of aquaculture expansion destroyed vast mangrove ecosystems. Current restoration efforts suffer from low sapling survival rates and conflicts with commercial shrimp farming interests.

Major commercial shipping ports across Southeast Asia lack elevated breakwaters and storm protection, risking catastrophic supply chain disruptions.

Surgeries designed to relieve nerve-related pain occasionally result in new or persistent pain instead, and predicting which patients are at risk remains imprecise. Better prediction and prevention could improve surgical outcomes for chronic pain patients.

A subset of patients with chronic acid reflux don't find adequate relief through standard medication, leaving surgery as one of the few remaining options. A more effective non-surgical treatment remains needed.

TMJ disorders can cause persistent jaw pain and dysfunction that current treatments, from mouthguards to surgery, don't reliably resolve for every patient. A more effective, universal treatment approach remains undeveloped.

Some patients experience persistent fatigue for months after major surgery that goes beyond typical recovery time, and the reasons for this aren't fully understood. Better prevention and treatment of post-surgical fatigue remains an underexplored area.

A subset of patients develop long-lasting pain after surgeries that are usually uncomplicated for most people, and the biological reason for this difference isn't fully understood. Better prediction and prevention could reduce this often overlooked outcome.

Some patients experience ongoing digestive issues after gallbladder removal, a very common surgery, and current understanding of why this happens in some but not others remains incomplete. Better prevention or treatment of these complications remains needed.

Recurrent tonsillitis in children often leads to tonsil removal because non-surgical prevention methods aren't reliably effective. A less invasive way to prevent recurrence remains undeveloped.

Confirming an endometriosis diagnosis often still requires invasive surgery, delaying treatment for patients who could benefit from earlier intervention. A reliable non-invasive diagnostic method remains an important unmet need.

Some patients with chronic sinusitis continue experiencing symptoms even after surgical intervention, suggesting current treatments don't address every underlying cause. A more complete understanding and treatment approach remains needed.

Even with strict sterile procedures, a portion of surgical patients still develop infections afterward, extending recovery and sometimes causing serious complications. Reducing this risk further remains an ongoing surgical challenge.