Addressing wildlife trade continuing is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
wildlife
trade
continuing
2030
implementing
mathematics-logic
fairtrade reaching few remains one of the most urgent challenges of our time. Systems currently in place are inadequate for the scale and complexity of the problem. A successful approach must work where resources are scarcest and demonstrate clear, measurable results. It should identify possible harms, respect local agency, and show how the solution can be maintained and expanded by the communities it is meant to serve.
fairtrade
reaching
few
implementing
proven
economics-resources
Automation may reduce routine collaboration and informal learning, especially for remote and platform workers. Future work design must preserve mentorship, belonging, collective problem-solving, and psychological health. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
europe
germany
preventing
social
isolation
highly
automated
workplaces
under
geopolitical
fragmentation
design
economics-resources
climate-environment
society-governance
systems
quantum
Addressing trade wars hurting the poor is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
capacity
trade
wars
hurting
poor
mathematics-logic
Addressing fair trade remaining rare is critical for achieving the 2030 Agenda. Current efforts fall short in scale, speed and equity, leaving the most vulnerable behind. Any viable solution must function in low-resource settings with limited specialists, transport, laboratory capacity and broadband. Proposals should specify quantifiable biological, social or environmental outcomes, openly discuss potential risks, and present a realistic pathway for long-term maintenance and local ownership beyond short research pilots.
fair
trade
remaining
rare
2030
mathematics-logic
Climate change and urban pumping changes may cause groundwater to enter basements, transit systems, utilities, and foundations. Cities need mapping, waterproofing, drainage, and financing strategies that address slow cumulative damage. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
asia
india
climate-change
groundwater
adapting
underground
infrastructure
rising
under
geopolitical
fragmentation
climate
change
technology-computing
climate-environment
society-governance
systems
The problem of the global arms trade continuing continues to affect hundreds of millions of people and undermines progress on multiple Sustainable Development Goals. Existing responses remain fragmented, under-resourced and poorly adapted to local contexts. A strong solution must operate effectively under severe constraints of skilled personnel, infrastructure, electricity and connectivity. It should define clear measurable outcomes, identify possible unintended harms, and demonstrate how the intervention can be sustained by local institutions long after initial funding ends.
global
arms
trade
continuing
creating
other
Decision-makers lack integrated, high-resolution models of ocean chemistry, biology, currents, and human activity. The open problem is building trustworthy systems that support decisions without creating false confidence from incomplete data. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
europe
norway
real-time
marine
ecosystem
digital
twins
under
geopolitical
fragmentation
data
decision-makers
economics-resources
society-governance
systems
climate-environment
infrastructure
Growing desalination could produce concentrated brine and chemical waste at scales that threaten coastal ecosystems. The challenge is improving recovery and discharge methods while accounting for cumulative regional impacts. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
asia
indonesia
desalination
brine
ocean
governance
under
geopolitical
fragmentation
growing
produce
concentrated
technology-computing
economics-resources
climate-environment
systems
quantum
Temporary or permanent height exchange for social or economic benefits creates new bodily hierarchies and health risks. The problem is protecting bodily integrity from becoming a tradable commodity linked to status.
height
preventing
advantage
markets
trade
economics-resources
If people live substantially longer, societies will need new models for work, learning, housing, dependency, and end-of-life care. Existing systems are not designed for decades of post-retirement life or multiple phases of dependency. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
asia
thailand
care
infrastructure
extreme
longevity
under
geopolitical
fragmentation
dependency
people
live
technology-computing
climate-environment
systems
society-governance
quantum
Lunar infrastructure and resource extraction could create new strategic inequalities. The challenge is developing rules that enable science and commercial activity while protecting shared interests and preventing territorial competition. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
oceania
australia
access
lunar
equitable
scientific
resources
under
geopolitical
fragmentation
create
infrastructure
technology-computing
climate-environment
society-governance
systems
quantum
open
United States, North America
Autonomous spacecraft may make split-second avoidance decisions using imperfect data and proprietary software. The unresolved problem is assigning responsibility, proving fault, and compensating affected parties across jurisdictions. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
technology-computing
north-america
united-states
autonomous
spacecraft
liability
collisions
under
geopolitical
fragmentation
data
may
make
economics-resources
climate-environment
society-governance
systems
infrastructure
open
South Africa, Africa
AI-designed biological molecules may be created faster than their safety, ecological, and clinical properties can be characterized. The open problem is building evaluation pipelines proportionate to capability and deployment risk. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
africa
south-africa
standards
ai-designed
proteins
under
geopolitical
fragmentation
deployment
biological
molecules
technology-computing
economics-resources
climate-environment
society-governance
systems
infrastructure
Large-scale fermentation may compete with food, land, and water if it depends on agricultural inputs. Future systems need safe, affordable, low-carbon feedstocks that do not shift environmental burdens to poorer regions. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
climate-environment
asia
india
feedstocks
biomanufacturing
non-food
under
geopolitical
fragmentation
large-scale
fermentation
may
compete
technology-computing
economics-resources
society-governance
systems
infrastructure
Biological design tools are becoming more accessible while oversight remains fragmented across countries and institutions. The challenge is detecting dangerous activity without suppressing legitimate research or creating an intrusive global surveillance system. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
mathematics-logic
asia
india
monitoring
synthetic
biology
risk
under
geopolitical
fragmentation
design
research
technology-computing
economics-resources
society-governance
climate-environment
systems
infrastructure
Future shocks may affect several producing regions simultaneously, making traditional diversification insufficient. The challenge is combining storage, alternative crops, trade rules, logistics, and social protection without creating waste or market distortion. The solution must work with limited capital, intermittent services, and local maintenance capacity. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
africa
kenya
supply-chain
climate-resilient
supply
chains
essential
foods
low-income
communities
future
shocks
may
technology-computing
climate-environment
society-governance
systems
Quantum capabilities could transform optimization, chemistry, intelligence, and cryptanalysis while becoming concentrated in a few states. The challenge is preventing destabilizing secrecy and unequal access without blocking peaceful scientific collaboration. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
asia
india
quantum
international
governance
advantage
under
geopolitical
fragmentation
access
capabilities
transform
technology-computing
economics-resources
climate-environment
systems
infrastructure
open
European Union, Europe
Frontier AI may become essential infrastructure controlled by a small number of governments or companies. The unresolved task is developing ownership, access, competition, and public-interest models that prevent private or geopolitical concentration from determining global outcomes. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
society-governance
europe
european-union
concentration
geopolitical
preventing
advanced
decision
power
under
fragmentation
access
frontier
technology-computing
economics-resources
climate-environment
systems
infrastructure
Future infrastructure will increasingly rely on systems capable of making decisions without immediate human supervision. The unresolved problem is creating architectures that can prove what they did, explain uncertainty, fail safely, and remain controllable during abnormal conditions. The design must remain functional when standards, trade routes, data access, and diplomatic cooperation are unreliable. The research opportunity is to define measurable success criteria, test the approach in realistic settings, identify failure modes, and create a pathway from prototype to accountable deployment.
economics-resources
asia
india
infrastructure
auditable
autonomy
critical
under
geopolitical
fragmentation
remain
future
will
technology-computing
society-governance
climate-environment
systems
quantum