A living repository of problems worth solving.
World Solve is an institutional, citable repository of unsolved and solved problems across science, technology, economics, governance, and philosophy. We give independent researchers and entrepreneurs precise targets to work on next.
1. Explore & Filter
Search and filter across continents, categories, and tags to find precise problems matching your expertise.
2. Claim & Work
Mark problems you are actively working on, collaborate with peers, and build verified solutions.
3. Citable Records
Every problem gets a unique permanent citation ID (e.g. WS00042) for research papers and proposals.
4194Total
4194Open
0Solved
9Humans
Open
Global / Global / Unspecified
WS00665
A few seconds of someone's voice is now enough to generate convincing fake audio of them saying anything, and current detection tools often fail to catch high-quality fakes in real time. This is already being used for financial scams target...
Team Humans Club. (2026). We can't stop deepfake voice cloning from being used convincingly for fraud and impersonation.. World Solve Repository, WS00665. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=665
Open
Global / Global / Unspecified
WS02020
Over the next two decades, rising resistance in bacteria, fungi, and parasites risks undermining surgery, chemotherapy, and intensive care. Global surveillance networks, rapid diagnostics, and new antimicrobial development platforms are cru...
Team Humans Club. (2026). Antimicrobial resistance could make routine infections deadly again. This variant focuses on data infrastructure and measurement challenges over the next two decades.. World Solve Repository, WS02020. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2020
Open
Global / Global / Unspecified
WS02021
Deforestation, wildlife trade, and dense urbanisation increase contact between humans and animal reservoirs, enabling novel pathogens to emerge. Planetary-health surveillance systems and adaptable vaccine platforms will be essential.
Team Humans Club. (2026). Future pandemics driven by zoonotic spillover are likely to become more frequent.. World Solve Repository, WS02021. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2021
Open
Global / Global / Unspecified
WS02022
Deforestation, wildlife trade, and dense urbanisation increase contact between humans and animal reservoirs, enabling novel pathogens to emerge. Planetary-health surveillance systems and adaptable vaccine platforms will be essential.
Team Humans Club. (2026). Future pandemics driven by zoonotic spillover are likely to become more frequent. This variant focuses on data infrastructure and measurement challenges over the next two decades.. World Solve Repository, WS02022. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2022
Open
Global / Global / Unspecified
WS02023
Ageing populations, urban diets, and pollution will drive surges in cardiovascular disease, diabetes, cancer, and chronic respiratory conditions. Scalable chronic-care models, digital coaching tools, and preventive policy reforms are needed...
Team Humans Club. (2026). Non-communicable diseases will dominate mortality in low-income countries by 2040.. World Solve Repository, WS02023. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2023
Open
Global / Global / Unspecified
WS02025
By the 2030s and 2040s, extreme heat and shifting mosquito ranges will expand malaria, dengue, and other infections into new regions. Heat-health early-warning systems and climate-sensitive disease-modelling platforms must be deployed.
Team Humans Club. (2026). Climate change will amplify heat-related illness and vector-borne diseases.. World Solve Repository, WS02025. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2025
Open
Global / Global / Unspecified
WS02027
Rising stress, social isolation, and economic precarity will increase depression, anxiety, and cognitive disorders, especially among youth. Scalable digital therapeutics and integrated community mental-health ecosystems are needed.
Team Humans Club. (2026). Mental health and neurodevelopmental disorders will be among the largest global health burdens.. World Solve Repository, WS02027. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2027
Open
Global / Global / Unspecified
WS02028
Rising stress, social isolation, and economic precarity will increase depression, anxiety, and cognitive disorders, especially among youth. Scalable digital therapeutics and integrated community mental-health ecosystems are needed.
Team Humans Club. (2026). Mental health and neurodevelopmental disorders will be among the largest global health burdens. This variant focuses on data infrastructure and measurement challenges over the next two decades.. World Solve Repository, WS02028. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2028
Open
Global / Global / Unspecified
WS02029
The share of people over 65 will rise sharply, raising demand for geriatric care, dementia services, and palliative care. Robotics-assisted caregiving, home-based monitoring, and new care-financing models could ease the burden.
Team Humans Club. (2026). Ageing populations will strain health systems and long-term care infrastructure.. World Solve Repository, WS02029. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2029
Open
Global / Global / Unspecified
WS02030
Genomic and biomarker-driven therapies will transform oncology and rare disease care, but high costs and limited capacity risk concentrating benefits in wealthy populations. Fair pricing, global data-sharing, and low-cost diagnostics will b...
Team Humans Club. (2026). Precision medicine will create new inequalities if access remains limited.. World Solve Repository, WS02030. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2030
Open
Global / Global / Unspecified
WS02032
By 2040, editing tools and gene drives could reshape ecosystems or be misused to create dangerous pathogens. Governance frameworks, secure design pipelines, and ethics review infrastructures are needed.
Team Humans Club. (2026). Synthetic biology and genome editing will raise complex biosecurity and ethical challenges.. World Solve Repository, WS02032. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2032
Open
Global / Global / Unspecified
WS02034
AI tools will increasingly support diagnosis and triage, but biases and opaque models may harm patients. Transparent validation frameworks, audit trails, and clinician–AI training curricula will be key.
Team Humans Club. (2026). Human–AI collaboration in clinical decision-making will need rigorous oversight.. World Solve Repository, WS02034. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2034
Open
Global / Global / Unspecified
WS02035
AI tools will increasingly support diagnosis and triage, but biases and opaque models may harm patients. Transparent validation frameworks, audit trails, and clinician–AI training curricula will be key.
Team Humans Club. (2026). Human–AI collaboration in clinical decision-making will need rigorous oversight. This variant focuses on data infrastructure and measurement challenges over the next two decades.. World Solve Repository, WS02035. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2035
Open
Global / Global / Unspecified
WS02036
Electronic health record silos, uneven standards, and privacy concerns will hinder cross-institutional analytics. Federated learning, privacy-preserving linkage, and open standards could unlock insights.
Team Humans Club. (2026). Data interoperability will remain a bottleneck for learning health systems.. World Solve Repository, WS02036. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2036
Open
Global / Global / Unspecified
WS02038
mRNA and vector-based technologies can shorten response times, but manufacturing capacity and regulatory agility must be built in advance. Global manufacturing networks and adaptive trial designs will matter.
Team Humans Club. (2026). Next-generation vaccine platforms must be ready to respond within weeks to new threats.. World Solve Repository, WS02038. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2038
Open
Global / Global / Unspecified
WS02039
mRNA and vector-based technologies can shorten response times, but manufacturing capacity and regulatory agility must be built in advance. Global manufacturing networks and adaptive trial designs will matter.
Team Humans Club. (2026). Next-generation vaccine platforms must be ready to respond within weeks to new threats. This variant focuses on data infrastructure and measurement challenges over the next two decades.. World Solve Repository, WS02039. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2039
Open
Global / Global / Unspecified
WS02040
Persistent symptoms after infections strain health systems and productivity, yet mechanisms are incompletely understood. Large longitudinal cohorts and mechanistic studies are needed to inform care pathways.
Team Humans Club. (2026). Long COVID and post-viral syndromes may remain a significant burden into the 2030s.. World Solve Repository, WS02040. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2040
Open
Global / Global / Unspecified
WS02041
Persistent symptoms after infections strain health systems and productivity, yet mechanisms are incompletely understood. Large longitudinal cohorts and mechanistic studies are needed to inform care pathways.
Team Humans Club. (2026). Long COVID and post-viral syndromes may remain a significant burden into the 2030s. This variant focuses on data infrastructure and measurement challenges over the next two decades.. World Solve Repository, WS02041. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2041
Open
Global / Global / Unspecified
WS02042
Mega-cities will produce unique mixtures of traffic accidents, air pollution, and sedentary lifestyles. Urban health observatories and built-environment intervention tools will be critical.
Team Humans Club. (2026). Urbanisation will drive new patterns of injury, pollution exposure, and lifestyle disease.. World Solve Repository, WS02042. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2042
Open
Global / Global / Unspecified
WS02044
Ultra-processed foods, changing agriculture, and altered gut microbiota may fuel future epidemics of obesity and metabolic disease. Microbiome-targeted therapies and nutrition-policy analytics will be important.
Team Humans Club. (2026). Food-system transformations will reshape human microbiomes and metabolic health.. World Solve Repository, WS02044. Retrieved from https://www.worldsolve.org/index.php?view=problem&id=2044
